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Bol. Oficina Sanit. Panam ; 105(5/6): 763-787, nov.-dic. 1988.
Article in Spanish | LILACS | ID: lil-367120

ABSTRACT

Animal models may be used for the study of HIV (human immunodeficiency virus) infection and AIDS (acquired immunodeficiency syndrome). Three major animal models that reproduce many aspects of HIV infection in man are available: infection by simian immunodeficiency viruses (SIV) and by non-primates lentiviruses, and HIV infection of non-human primates. The use of primate and nom-primate lentivirus models is critical for the continued development of vaccines and therapeutics for AIDS. This Memorandum describes the present situation in this área of research, as reported by the participants at a WHO Consultation in Geneva, Switzerland, in March 1988, and includes their recommendations


Subject(s)
Acquired Immunodeficiency Syndrome , Disease Models, Animal , Deltaretrovirus Infections/immunology , Acquired Immunodeficiency Syndrome/therapy , Macaca , Pan troglodytes , Papio , Primates , Retroviridae Infections , Viral Vaccines/isolation & purification
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