ABSTRACT
With the development of mass spectrometer,protein and peptide separation technology,and data analysis tools,the study on protein expression profiling of various tissues,organs or cells has been developed rapidly.The most basic purpose of proteomics is qualitative and quantitative identification of the whole protein in a cell or tissue.Therefore,how to make full use of mass spectrometry data has an important significance in proteome.Recently years,proteomics has begun to be applied in allograft rejection and discovery of rejection related biomarkers in organ transplantation.Through the extensive application of the technology in organ transplantation,graft rejection can be earlier detection and treatment.Therefore,the proteomics research have potential application prospects in the diagnosis of the organ transplant rejection.