ABSTRACT
Objective To analyze the clinical characteristics and risk factors of multiple drug -resistant bacteria infection in patients with diabetic foot .Methods The clinical data of 60 patients with diabetic foot were retrospectively analyzed , including diabetic foot infected ( positive group ) and uninfected multiple drug -resistant bacteria(negative group),30 cases in each group.Application of SPSS 17.0 statistical software for infection and clinical characteristics of the single factor analysis , through the Logistics regression analyzed the risk factors of infection . Results A total of 130 strains bacteria were isolated in the positive group ,of which more than 64 strains of drug-resistant bacteria,the detection rate was 49.23％;The top three for staphylococcus aureus (60.00％),enterobacter (53.33％) and verdigris pseudomonas (31.57％).Single factor analysis results showed that age , hypertension between the two groups had no statistically significant differences (all P>0.05);Positive group in the use of antibiotics prior to admission time,ulcerated area,etc.,compared with the negative group the differences were statistically significant (t=1.812, -7.268,all P <0.05).Multiple factors analysis showed that admission ,antibiotics,ulcerated area, osteomyelitis were risk factors of positive infection in patients .Conclusion The risk factor resulted in diabetic foot patients infected multiple drug -resistant bacteria is more ,and the amputation rate of patients with infection group is obviously higher than that of patients who are not infected ,to ensure that the prognosis of patients with diabetic foot level,should strengthen the control of multiple drug -resistant bacteria infection ,thus to better achieve treatment goals .
ABSTRACT
Objective In order to study the etiology and the hearing status of the deaf students in Hubei province, a survey was carried out from April 1999 to June 2000.Methods A total number of 813 deaf students in Hubei province were examined with audiometer and investigated through questionnaire. The pedigress analysis was conducted in deaf students with family history.Results The pedigrees of 227 familes with deafness were obtained, the inheritance pattern of 167 families could be ascertained. 232(28.5%) deaf students were diagnosed congenital deafness, 581 (71.5%) students were diagnosed acquired deafness. The degrees of deafness could be ascertained with 359(44.1%) students of profound deafness, 323(39.7%) students of severe deafness, 111(13.7%) students with moderate to severe deafness, 11(1.4%) students of moderate deafness, and 9(1.1%) students of mild deafness.Conclusion The hearing loss of deaf students is very serious, and genetic factor and ototoxic antibiotics were a principal causation in the occurrence of deafness.