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Objective To understand the status of Toxoplasma gondii infection in women with adverse pregnancy outcomes in Longhua region,Hebei Province. Methods A total of 393 women with adverse pregnancy outcomes were chosen as respon-dents in the Longhua County Maternal and Child Health Care Center between January 2013 and June 2016 and were divided into an acute infection group,a previous infection group,and an active infection group according to the test results. Totally 256 wom-en without adverse pregnancy outcomes were selected as a control group. IgM and IgG antibodies to T. gondii were detected by using ELISA in each group. The risk factors of T. gondii infection were surveyed by questionnaires. Results The T. gondii infec-tion rate of the women with adverse pregnancy outcomes was 27.23%(107/393),which was significantly higher than 8.20%(21/256)in the control group(χ2=35.46,P<0.01). The rates of acute infection,previous infection,active infection in the wom-en with adverse pregnancy outcomes were 6.87%(27/393),18.58%(73/393),and 2.54%(10/393)respectively,which was significantly higher than those[1.17%(3/256),7.03%(18/256),0(0/256)]in the control group(χ2=11.43,17.15,7.90 re-spectively,P<0.01). The ratios of the career in contact with raw meat,feeding pets(dog and cat),tasting raw meat,chopping board regardless of uncooked or cooked food,frequently eating rinsing boiler or barbecue,frequently eating outside of the wom-en with T. gondii infection were significantly higher than those of the women without T. gondii infection(χ2 =12.08,29.23, 8.55,13.41,7.28,6.06 respectively,P<0.01 or 0.05). Conclusions T. gondii infection could lead to serious adverse preg-nancy outcomes. Therefore,to avoid contacting with pets,not eating undercooked food,and strengthening personal health pro-tection are the important keys to avoid T. gondii infection.
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Objective To investigate the factor that affecting the prevalence of osteoarthritis in rural areas of Shanxi, China. Methods All the residents above 16-year-old from the villages chosen by multi-stage stratified cluster sampling in Yangcheng County and Pianguan County in Shanxi Province were investigated by COPCORD procedure of WHO. All respondents signed the informed consent forms. Chi-square test and multivariable logistic regression analysis were used for the risk factor analysis. Results Seven thousand one hundred and twenty-six permanent residents in the two counties were investigated, of which 1734 cases of patients with osteoarthritis were identified. Take with or without osteoarthritis as response variables, statistically significant variables in the univariate analysis were substituted into the logistic regression model. Forward method was used for the variable selection. The inclusion criteria set as 0.10. The results showed that, age, room heating and ventilation, marital status, occupation, education, engaged in coal mine work, accompanied cardiovascular disease were the risk factors for osteoarthritis disease. Conclusion There were many factors that affect the prevalence of osteoarthritis in Shanxi rural communities, in which lifestyle may play an important role. Early intervention on risk factors may have a significant effect on reducing the prevalence.
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Objective To clarify the effec.t of smoking and related factors in symptomatic osteoarthritis disease,and explore the method to analyze the osteoarthritis (OA) risks.Methods Based on the investigation of 7 126 rural residents in Shanxi province,according to whether patients had related factors of symptomatic osteoarthritis in longitudinal axis arthrosis,the single factor and multiple factors logistic regression analysis were adopted to reveal the interaction between risk factors,and the interaction on multiplicative scale and the interaction on additive scale were both analyzed;interaction on multiplicative scale was estimated by OR,the interaction on additive scale was estimated by the relative excess risk due to interact (RERI),the attributableproportion due to interaction (AP),and the synergy index (S).Results The survey included 7 126 residents,in which 1 480 cases osteoarthritis patients in vertical axis joint with the prevalence of 20.8％.By multiple logistic regression analysis,the whole samples by enter level 0.05 level was stepwisely filtered.The results showed that gender,body mass inlex (BMI),smoking,age,heatable adobe,picky eater,working under coal mine were main influencing factors for the symptomatic arthritis.Balance other influence factors,passive smoking had an effect on arthritis.Aftcr adjusting for weight,smoking was not included in the final model.In the stratified interaction analysis,there was interaction on multiplicative scale between smoking and weight (OR=0.32,P=0.03),and the interaction on additive scale between passive smoking and gender or weight exists [RERI (95％CI) 0.41 (0.01,0.81)＞0,AP(95％CI) 0.25(0.01,0.51)＞0,S=3.04＞ 1].Conclusion The influence of smoking on osteoarthritis is so weak that it could not be a risk factor and its influence on osteoarthritis is initiated via body.
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Objective To clarify evaluation methodology of the accuracy of differential diagnosis of meningioma and glioma,taking magnetic resonance imaging (MRI) and vascular endothelial growth factor (VEGF) into account.Methods According to the unified standard of design,114 cases were selected,which were diagnosed by postoperative pathological in Shanxi Cancer Hospital from March 2010 to October 2012.On the basis of hospital routine inspection,all patients needed MRI scan,enhancement scan,VEGF,ALP and LDH,with pathological diagnosis of glioma or meningioma.Using ROC curve analysis which took VEGF,T2WI into account,the accuracy of differential diagnosis could be evaluated.Results The results showed that the differential diagnosis accuracy were high relatively,the area under the ROC curve was 91.34 ％.When the T2WI were equisignal,low signal or high signal respectively,the area under the curve ROC were 97.62 ％,90.00 ％,88.34 ％.Conclusion To consider the MRI T2WI and VEGF,ROC curve regression model analysis can enhance the differential diagnosis accuracy of meningioma and glioma.
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Objective To study the prevalence of symptomatic osteoarthritis (OA) in rural areas of Shanxi,China.Methods All the residents above 16 years old from the villages chosen by multi-stage stratified cluster sampling in Yangcheng County and Pianguan County in Shanxi Province were investigated with COPCORD procedure of WHO.All the respondents signed the informed consent forms.All statistical analysis were carried out using SAS 9.2 and SPSS standard version 13.0.Chi-square test was used for statistical analysis.P value ＜0.05 was regarded as statistically significant.Results The investigation in these two counties covered 7 126 residents,including 1 734 symptomatic OA patients,with a prevalence rate of 24.3％,where knee OA had the highest prevalence rate [13.8％(983/7 126)],other figures were as follows:lumbar vertebra,neck,hand,shoulder,elbow,ankle,hip,wrist,thoracic vertebra and foot.There were statistical differences in the prevalence of knee,ankle,neck,shoulder and hand between the two genders (P＜0.05).Conclusion The prevalence of symptomatic OA in rural areas of Shanxi,China is relatively high,but the risk factors still need to be further studied and proved.
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@#cases were classified by using RUGⅢ.The result indicates that RUG Ⅲ is objective to re-flect all reasonable costs for clients.It has therotical and practical significence to research RUG Ⅲ for institu-tions involving rehabilitation,family beds and deathbed care.