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1.
Journal of Pharmaceutical Practice ; (6): 75-77, 2017.
Article in Chinese | WPRIM | ID: wpr-790703

ABSTRACT

Objective To evaluate the effects of fentanyl transdermal combined with morphine subcutaneous injection in the management of advanced liver cancer pain after intervention .Methods 166 patients who suffered from advanced liver canc-er and received intervention therapy in our hospital were divided into two groups .89 patients belong to the fentanyl transdermal combined with morphine subcutaneous injection treatment group .77 patients belong to the morphine subcutaneous injection treatment group .The pain score and the remission rate of the two groups were compared and analyzed statistically .Mean-while ,the side effects of each group were recorded .Results Pain score in the group with fentanyl transdermal and morphine treatment was significantly lower than morphine mono therapy .12 hours after intervention therapy ,(1 .97 ± 0 .56 for combina-tion treatment vs 3 .23 ± 1 .49 for morphine only group ,P<0 .05) .24 hours after intervention therapy ,(1 .63 ± 0 .44 for com-bination vs 4 .19 ± 1 .68 for morphine only group ,P<0 .01) .Similarly ,the remission rate of the fentanyl transdermal combined with morphine subcutaneous injection group improved significantly ,(92 .1% vs 76 .6% P<0 .05) 12 hours after intervention therapy ,and(97 .8% vs 70 .1% ,P<0 .05) 24 hours after intervention therapy .Conclusions The addition of fentanyl trans-dermal to morphine subcutaneous injection treatment significantly improve the pain remission rate for the patients with advanced liver cancer pain 72 hours after intervention therapy .

2.
International Journal of Traditional Chinese Medicine ; (6): 902-904, 2016.
Article in Chinese | WPRIM | ID: wpr-504189

ABSTRACT

Objective To evaluate the effect of acupuncture for the stroke patients with tinnitus, hearing loss by using the twirling reinforcing method. Methods A total of 92 tinnitus, hearing loss patients with stroke were included and divided into the observation group and control group by random number table method, 47 in the observation group and 45 in the control group. Patients in both groups were needled at Tinggong, Tinghui, Yifeng in the affected side, and Zhongzhu, Waiguan, Sanyinjiao, Taichong and Taixi in both sides. Patients in the observation group were needled at Taixi and Sanyinjiao using the twirling reinforcing method, but those in the control group needled at Taixi and Sanyinjiao using the needle retention method. Patients in both groups were also treated with semiconductor laser therapy and ultrashort wave therapy. All patients were treated for 20 days. The Tinnitus Severity Scale and the clinical effect were evaluated. Results After the treatment, the Tinnitus Severity Scale scores in the observation group were significantly lower than that in the control group (5.04 ± 3.24 vs. 5.67 ± 3.55; t=-0.880, P>0.05). The improvement rate in tinnitus in the observation group was significantly higher than that in the control group (38.3%vs.17.8%;χ2=17.391, P=0.000). The improvement rate in hearing loss showed no significant difference between two groups (38.3%vs. 31.1%;χ2=8.522, P=0.004). Conclusions Acupuncture using the twirling reinforcing method may relieve tinnitus of the stroke patients with tinnitus, hearing loss.

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