ABSTRACT
A 15 year old male patient was diagnosed as being infected with the nematode Lagochilascaris minor, presenting as abscesses over the left mastoid region, and invading the temporal bone, mastoid sinuses and possibly the CNS. Surgical drainage and administration of cambendazole and levamisole led to improvement, followed by an early relapse and poor tolerance to the antihelminthic drugs. Repeated doses of ivermectin (an animal preparation) were used for the first time to treat this condition and resulted in complete remission of signs of infection, maintained for 15 months after the end of drug therapy, indicating cure of the disease.
Subject(s)
Humans , Animals , Male , Adolescent , Ascaridiasis/drug therapy , Drug Therapy, Combination , Ascaridia , Cambendazole , Drainage , Ivermectin , LevamisoleABSTRACT
Foram tratados neste estudo 30 doentes portadores de quadros infecciosos otorrinolaringofaríngicos com o PPA, por via oral, na dose de 400 mg a cada 12 horas, durante 10 dias. Os resultados globais obtidos expressam que houve uma remissäo completa dos sinais e sintomas em 21 doentes, sendo que em 7 casos a remissäo parcial dos sinais e dos sintomas justificou prosseguimento terapêutico. O índice global de efetividade terapêutica revelado neste estudo foi, portanto, de 93%