ABSTRACT
Background: The objective of our study is to check the incidence of various congenital fetal anomalies in antenatal period by ultrasonography in a subset of population.Methods: This cross sectional study was conducted in the department of Radiology, Bolan Medical Complex Hospital Quetta from November 2017 to October 2018. Total of 1323 second and third trimester pregnancies were analyzed for a period of one year. 34 fetal anomalies were detected making the prevalence of 2.5%. Information obtained from history, clinical examination and Ultrasound examination were recorded. The data was analyzed in SPSS 20.These patients were also interviewed for folic acid supplementation and consanguineous marriage.Results: 1323 patients were examined with congenital abnormalities detected in 34 fetuses. Among 34 fetuses, 20 were male and 14 were female fetuses. Out of 34, mother of 24 fetuses verified that they did not take folic acid supplementation. Consanguineous marriage recognized as the important risk factor as found in 22 congenital abnormal fetus. CNS anomalies were the most commonly occurring anomalies with prevalence of (0.9%) followed by gastrointestinal tract anomalies (0.3%) and Urinary tract anomalies (0.3%).Conclusions: The fetus prognosis largely depends on early detection of its any congenital anomaly on antenatal ultrasound as they can result in abortions, still births and other fetal defects. So antenatal ultrasound is very important and safe method for early detection and management of fetal anomalies.
ABSTRACT
Background: In Asia, Pakistan has the highest incidence of breast cancer with 1 in 8 women will develop breast cancer at some stage of their life. Delays in presentation and diagnosis are major determinants of breast cancer survival, but these have not been comprehensively investigated in Pakistan.Methods: A cross-sectional study was done from June 2017 till October 2018 at Radiology department of Bolan medical complex hospital in Quetta, Pakistan. Patients with breast cancer above the age of 18 and below 70 years were interviewed who were diagnosed with breast cancer. The time interval between self-detection and deciding to seek care was defined as delayed if the woman presented to a health care professional three months or more after detecting an abnormalityResults: A total of 86 breast cancer patients fulfilling the criteria were included in the study. Of these, 34% presented to physician within 3 months of appearance of symptoms, 68% patients presented with a delayed of more than 3 months. Presentation delay was due to financial issues which were seen in 30 patients. 18 patients (20.9%) showed delayed to due difficulty in reaching hospitals, 16 patients (18%) stated delay due to prior use of alternative therapies. Embarrassment and spiritual belief constituted 4.6% cases. 51% and 36% presented with stage III and IV disease out of which majority belonged to poor socio-economic status.Conclusions: The findings suggest that majority of the patients with breast cancer presented late and this has significant effect on their disease prognosis. Most cases of breast cancer presented in advanced stage probably due to poor economic status, difficulty in reaching hospital, illiteracy and negligence by patient or family.