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Objective:To investigate the characteristics, drug resistance and influencing factors of pathogenic bacteria in patients with infective endophthalmitis after cataract surgery.Methods:From September 2015 to September 2019, 800 patients with phacoemulsification and cataract extraction were selected from Zhejiang Provincial General Hospital of the Armed Police.According to whether there was postoperative infectious endophthalmitis, they were divided into infection group(13 cases) and non infection group(787 cases). After operation, patients with infective endophthalmitis underwent anterior chamber and/or vitreous puncture, aseptic samples were collected to isolate and identify the pathogenic bacteria, and the drug resistance was detected by paper diffusion method.Multivariate logistic regression was used to analyze the risk factors of postoperative infectious endophthalmitis.Results:In 13 cases of postoperative infective endophthalmitis, 14 strains of pathogenic bacteria were isolated.The resistance rate of Staphylococcus epidermidis to erythromycin was 57.14%.Single factor analysis showed that there were no statistically significant differences between the two groups in gender, BMI, hypertension, surgical incision and length of stay(all P>0.05). The infection rate of patients over 60 years old(3.11%) was higher than that of patients under 60 years old(0.45%), the infection rate of patients with diabetes mellitus(6.15%) was higher than that of patients without diabetes mellitus(1.22%), the infection rate of patients with operation time over 20 min (6.98%) was higher than that of patients with operation time under 20 min (0.98%). The infection rate of vitreous overflow(7.55%) was higher than that without vitreous overflow(1.20%). The differences were statistically significant(χ 2=8.728, 6.256, 13.717, 8.801, all P<0.05). The multivariate logistic regression analysis showed that age>60 years old, diabetes mellitus, operation time>20 min and vitreous overflow were the risk factors of postoperative infectious endophthalmitis. Conclusion:In order to reduce the incidence of infectious endophthalmitis, it is necessary to take preventive measures.
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Objective To investigate the protective effect of mucopolysaccharide polysulfate cream(MPC) and micro needle array drug delivery technologarray(MNADDT) on the blood vessel of arteriovenous fistula.Methods Eighty cases maintenance hemodialysis patients with autogenous arteriovenous fistula were randomly divided into control group(with the treatment of MPC) and study group(with the treatment of MPC plus MNADDT),40 patients in each group.Both groups were studied for the duration of 12 months.The vascular complications of puncture pain sense,puncture failure times,phlebitis,hardening of the arteries,internal fistula stenosis or embolism,pseudoaneurysm,swollen hands comprehensive syndrome of two groups were observed,and the changes of arteriovenous fistula blood flow,blood vessel diameter by Doppler ultrasound were observed in the two groups for 12 months.Results (1)The incidence of puncture pain(2.71±0.11 vs.2.76±0.14,t=2.21,P<0.05),puncture failure times(38 times vs.73 times,χ2=11.425,P<0.05),phlebitis(2 cases vs.8 cases,χ2=4.341,P<0.05) and blood vessel sclerosis(2 cases vs.9 cases,χ2=5.446,P<0.05) of the treatment group were significantly lower than that of the control group during the study(P<0.05).(2)Blood flow of arteriovenous fistulain of control group before and after treatment were (859.7±148.3) ml/min and (946.5±169.2) ml/min respectively,and the difference was significant(t=2.356,P<0.05).While blood flow of arteriovenous fistulain,cephalic vein diameter,head of venous flow velocity of study group before and after treatment were (824.6±171.5) ml/min and (1 218.1±241.9) ml/min,(5.59±0.74) mm and (6.02±0.57) mm,(94.23±27.35) cm/s and (115.85±36.63) cm/s,respectively,and the differences were significant(t=8.212,2.382,2.877,P<0.05),there were no significantly changes in the above indexes in the study group after treatment(t=5.3612,2.152,2.281,P<0.05).Conclusion MPC plus MNADDT can reduce the vascular complications of arteriovenous fistula,improve blood vessel diameter and increase blood flow.
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Refractive surgery for myopia is a common operation and has been performed on millions of patients .Improved technology has increased the satisfaction of patients and physicians .Surgery must follow the basic requirements of medical ethics , to ensure the safety and best interests of the patients .The choice of procedure depends on individual patient indications and ocular exami -nations .Before the surgery , the opthalmologists must ensure that the patient understands the potential risk of the operation and has re -alistic expectations for the visual acuity postoperatively .