ABSTRACT
Objective:To explore the effect of Xuanbai-Chengqi Decoction combined with conventional western medicine therapy for the coma patients with acute cerebral infarction. Methods:A total of 72 patients with acute cerebral infarction in Huaibei Hospital of Traditional Chinese Medicine from March 2019 to January 2020 were randomly divided into two groups with 36 in each group. The control group was treated with conventional western medicine therapy, and the treatment group was given Xuanbai-Chengqi Decoction by nasal feeding on the basis of the control group. Both groups were treated for 7 days. The National Institutes of Health Stroke Scale (NIHSS) was used to evaluate the degree of neurological deficit, and the Full Outline of Unresponsiveness Scale (FOUR) was used to evaluate the degree of consciousness disorder of patients. Three-dimensional reconstruction of head CT was performed to identify and mark the edema area. The levels of serum high-sensitivity C-reactive protein (hs-CRP), homocysteine (Hcy) and vascular endothelin-1 (ET-1) were measured by double antibody sandwich enzyme-linked immunosorbent assay. The adverse events during treatment were observed and the clinical effective rate was evaluated. Results:The total effective rate was 100% (36/36) in the treatment group and 86.1% (35/36) in the control group, and the difference between the two groups was statistically significant ( Z=-0.242, P=0.015). On the 3rd and 7th day after treatment, the NIHSS scores of the treatment group were significantly lower than those in the control group ( t values were 26.567 and 17.982, all Ps<0.01). On the 3rd and 7th day after treatment, the eye opening response, motor response, brainstem response, brain stem response and total scores (3 days after treatment, t=15.235 , 14.892, 18.452, 11.232, 16.235; 7 days after treatment, t=19.5 68, 16.232, 10.356, 9.546, 11.098) of the treatment group were significantly lower than those in the control group. The levels of serum hs-CRP, Hcy, ET-1 and CT threshold of brain edema in the treatment group were significantly lower than those in the control group after treatment ( t=22.352, 17.789, 11.908 and 19.652, all Ps<0.01). There were no adverse drug reactions, no abnormal changes in blood routine tests, liver function and electrocardiogram in both groups. Conclusion:The Xuanbai-Chengqi Decoction combined with conventional western medicine therapy can improve the neurological function and promote awakening of coma patients with acute cerebral infarction, which may be related to reducing the levels of inflammatory cytokines related to hs-CRP, Hcy and ET-1, improving microcirculation and relieving brain edema.
ABSTRACT
Objective] Analysis of the professor Hu using harmony method characteristics and curative effect. [Methods] Select master Hu ’s recipes of harmony method in his lifetime, and then analyze the characteristics and treatment effect. [Results] Master Hu in its many years of clinical process, with harmony method, repeatedly performs outstanding service, with particular emphasis on the day, people's unity, combined with good disease, four diagnostic methods. [Conclusion] Most of the patients recovered heathy, her characteristic treatment was worthy of deep reflection and research.
ABSTRACT
The McAb and APAAP method were used in the studies on the expression of some lym-phocyte associated antigens(CDs)and HLA—DP in the human fetal liver of 6—11 wks,emby roniclage,It is showed that to CD7~+,or CD2~+ cells was detected in fetal liver of 6—11 wks,indi-cating that probably no in-suit generating of T lymphocyte occured in human early fetal liver.The expression of some B lymphocyte associated antigens was found to be varied.No CD19~+,CD20~+ or CD22~+ cells was observed.As contrast,The CD9~+ CD10~+ and CD38~+ cells were found with increased percentage during 6 to 11 wks in fetal liver,this suggest that these three antigens appeared before the presence of pre—B cells in fetal liver.CD9,CD10 and CD38 antigens,being found existing in cells which varied in size and shape,probably are the common antigens shared by progenitors of more than one lineages of hemapoietic cells in fetal liver.The histocompatibility antigen HLA—DP is also positive during 6—11 wks.In frozen scetions,the CD9 ~+,CD~+,CD38~+and HLA—DP~+ cells were scatted singly over the fetal liver in random.But after 8 or 10 wks ofgestational age,some positiwe cells aggregations were found,probably indicating the prolifera—tion of these cells.
ABSTRACT
The development of pre-B cells in human early fetal liver(6-11wks)was studied by using anti-McAb,combined with APAAP method.The results showed that pre-B cells,including two subpopulations(round and elliptic),appeared first in one of 6.7 wks fetal liver and then in all specimens from week 7 to 11.The differentiated stage of elliptic pre-B cells was possibly arlier than the round ones.The amount of ?~+ cells arised continuly during the 7th to 11th week.Those cells were scattered singly over the liver,and no pre-B cells proliferation was observes.