ABSTRACT
Objective To study the closure time of neonatal ductus venosus and the Z score regression equation, and to explore the variation of closure time of neonatal ductus venosus with gestationalage.Methods Color doppler ultrasound was applied to detect the closure time of neonatal ductus venosus in normal newborns, Z score regression equation ( lnY =a +bX +cX2 ) for the closure time of neonatal ductus venosus ( Y ) was developed by regression analysis which used gestational age ( X) as an independent variable. The Z scores of the closure time of neonatal ductus venosus in different gestational age were calculated by the formula [ Z = ( M - Y )/S x , M for observation value, Y for predictivevalue].Results There were 432 cases in our study.The closure time of neonatal ductus venosus was negatively related to gestational age ( r = -0. 938 , P <0. 001 ) . The nonlinear regression equation was lnY= -5. 228+0. 089X-0. 000228X2, R2 =0. 854, Sx =0. 214(P<0. 001). Based on the predicted mean of the closure time and Sx related to different gestational age, Z scores for specific closure time of neonatal ductus venosus could be calculated by the formula [ Z =( M -Y)/Sx ] . The Z scores were normally distributed,and did not change with gestational age.Conclusions Theclosure & nbsp;time of neonatal ductus venosus is negatively related to gestational age. The Z scores obtained by the predicted nonlinear regression equation are normally distributed.
ABSTRACT
Objective To evaluate the value of using the color Doppler ultrasound in the treatment of pseudoaneurysm with thrombin intratumoral injection.Methods Intratumoral injection of thrombin was given under the guidance of color Doppler to 7 cases of femoral artery pseudoaneurysm after cardiac catheterization,then we observed thrombus formation time and the dosage of thrombin.After the treatment of 10 minutes,1 day,5 days,15 days,we reviewed pseudoaneurysm with the color Doppler ultrasound.Results Thrombosis in the pseudoaneurysm was fast with only 2 to 4 minutes,and thrombin dosage was 200 to 500U,with an average of 280 U,and the cure rate was 100%,but one case was accompanied by acute allergic reaction and ipsilateral deep venous thrombosis.Conclusion The color Doppler ultrasound-guided thrombin intratumoral injection treatment of pseudoaneurysm is a simple,safe and effective method,with few complications,so it can be used as the first choice treatment for pseudoaneurysm.