ABSTRACT
Objective To characterize the MRI features of demyelinating pseudotumors(DPTs).Methods MR data of 10 cases clinically proved with DPTs were retrospectively analyzed .All cases were underwent MRI scan ,9 of 10 cases were performed with enhanced MRI,7 cases were underwent diffusion weight imaging(DWI),2 cases were performed with single voxel short echo 1 H-MRS.Results 8 cases showed lesions with mild to moderate edema,5 cases showed multiple lesions,3 cases were solitary nodular lesions,2 cases were solitary flaky lesions.On enhanced MRI,4 cases presented with open ring like enhancement,3 cases presented ring like enhancement,1 case with nodular enhancement,and 1 case showed patchy enhancement.All lesions showed high signal in DWI.In 1 H-MRS,2 cases demonstrated varying decrease in peaks heights of Nacetylaspartate(NAA),elevation of the choline(Cho),the lactate(Lac)and lipids(1ip).1 case demonstrated evident elevation in peaks height of glutamate/glutamine(Glx).Conclusion DPTs has some characteristics on MRI, especially as open ring like enhancement.It is helpful to identified DPTs from other lesions when together with DWI and 1 H-MRS.