ABSTRACT
Breast cancer is the most common cancer in females in the world. Breast aspiration cytology, histopathology and radiology have become important diagnostic tools in diagnosis of breast cancers. Objectives: Our aim was to conduct a combined diagnostic approach comprising of clinical examination, mammography, fine needle aspiration cytology and histopathology study in breast cancers correlate with individual diagnostic modality. Methods: A prospective study was done on 100 patients suspected of breast cancer. Various investigations including radiological investigations, FNAC, biopsy of the lesion was done. Clinical diagnosis, radiological, cytological and histopathology results were combined and compared with individual diagnostic modality. Results: Most common presenting symptom was breast lump seen in 95 cases. Out of 100 cases 47% were diagnosed malignant on radiology, 71% were malignant on Fine Needle Aspiration Cytology and 85% were diagnosed malignant on biopsy. On comparing all the three diagnostic procedures (radiology, FNAC and biopsy), the correlation came out to be highly significant. Conclusion: Though histopathological examination remains the gold standard for the diagnosis of these lesions, but an accurate clinical, radiological and cytological combined approach along with the histopathological examination aids in improving the diagnostic accuracy and reduce morbidity and mortality.
ABSTRACT
Background: Women worldwide suffer from various gynaecological disorders that require hysterectomy as a treatment option. Objectives: Our aim was to conduct a histopathological study of various uterine lesions in hysterectomy specimens and to correlate the findings with clinical indications. Methods: A prospective study was done on 200 hysterectomy specimens. The specimens were fixed in formalin and the tissue was adequately processed. The sections were stained with routine Haematoxylin and Eosin stain. Results: In this study the most common clinical indication for hysterectomy was leiomyoma (57.0%) followed by utero-vaginal prolapse (28.5%). Clinical indication of leiomyoma was confirmed by histopathology in 96.5% cases, whereas that of cervical dysplasia, cervical polyp, squamous cell carcinoma cervix, chronic pelvic inflammatory disease, adenomyosis and endometrial carcinoma was confirmed in 100% cases. Conclusion: The ultimate diagnosis and prognosis depends on the histopathological examination; therefore every operated specimen must be subjected to histopathology.