Utility of diffusion weighted magnetic resonance imaging with multiple B values in evaluation of pancreatic malignant and benign lesions and pancreatitis

Objective: To determine the feasibility of diffusion-weighted imaging in evaluation of pancreatic lesions and in differentiation of benign from malignant lesions

Study Design: Descriptive study

Place and Duration of Study: Baskent University Adana Teaching and Research Center, Adana, Turkey, between September 2013 and May 2015

Methodology: Forty-three lesions [pancreas adenocarcinoma [n=25]], pancreatitis [n=10], benign lesion [n=8]] were utilized with diffusion-weighted magnetic resonance imaging with multiple b-values. Different ADC maps of diffusion weighted images by using b-values were acquired

Results: The median ADC at all b values for malignant lesions was significantly different from that for benign lesions [p<0.001]. When ADCs at all b values were compared between benign lesions/normal parenchyma and malignant lesions/normal parenchyma, there was a significant statistical difference in all b values between benign and malignant lesions except at b 50 and b 200 [p<0.05]. The lesion/normal parenchyma ADC ratio for b 600 value [AUC=0.804] was more effective than the lesion ADC for b 600 value [AUC=0.766] in differentiation of benign and malignant lesions. The specificity and sensitivity of the lesion/normal parenchyma ADC ratio were higher than those of ADC values of lesions. When the ADC was compared between benign lesions and pancreatitis, a significant difference was found at all b values [p<0.001]. There was not a statistically significant difference between the ADC for pancreatitis and that for malignant lesions at any b value combinations [p>0.05]

Conclusion: Diffusion-weighted magnetic resonance images can be helpful in differentiation of pancreatic carcinoma and benign lesions. Lesion ADC / normal parenchyma ADC ratios are more important than lesion ADC values in assessment of pancreatic lesions

Abdominal CT findings in patients with primary lymphoma causing small bowel obstruction

The purpose of this study was to investigate retrospectively CT findings in patients with primary lymphoma causing small bowel obstruction. CT scans of 11 patients with small bowel lymphoma were separately analysed in terms of affected section of the small bowel, focality, wall thickness, pattern and degree of contrast enhancement, lymphadenopathy, organ involvement, perforation, and the presence of intraabdominal fluid. Eight patients had diffuse large B-cell lymphoma, and one patient each had marginal zone lymphoma of mucosa-associated lymphoid tissue [MALT], T-cell lymphoma, and anaplastic T-cell lymphoma. Affected sections of the bowels involved were jejunum [n=5, 45.4%], ileum [n=2, 18.1%], and one case [9%] each of distal ileum, distal jejunum, distal jejunum and ileum, and distal jejunum and colon. Primary gastrointestinal [GI] lymphoma is an uncommon disease, that may lead to small bowel obstruction sometimes