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IJRM-Iranian Journal of Reproductive Medicine. 2013; 11 (8): 653-658
in English | IMEMR | ID: emr-130767

ABSTRACT

Present study was conducted to observe the effects of testosterone, nandrolone, and stanozolol [forms of AAS] intake during onset of puberty on the rat testicular histology. Juvenile male Sprague-Dawley [SD] rats [n=42] were divided into seven groups and were injected subcutaneously with medium dose of polyethylene glycol-200 [PEG-200] [control], testosterone, nandrolone, and stanozolol for six weeks [PND 41-87]. The animals were weighed daily and sacrificed on PND 88. Testes were removed, weighed, and prepared for histological assessment and finally specimens were observed under microscope. The results showed an insignificant increase in mean daily body weight with highest and lowest body weight gained was of 177.6 +/- 1.69 gr and 140.0 +/- 12.26 gr respectively. There was significant decrease in the testes absolute weight [p

Subject(s)
Male , Animals, Laboratory , Testosterone , Nandrolone , Stanozolol , Rats, Sprague-Dawley
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