Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 3 de 3
Filter
1.
Pediatric Allergy and Respiratory Disease ; : 283-291, 2008.
Article in Korean | WPRIM | ID: wpr-180642

ABSTRACT

PURPOSE: The incidence of food allergy associated with atopic dermatitis is approximately 40-60%. We evaluated serum specific IgE to cow's milk (CM), egg white (EW) and soybean in atopic dermatitis and then compared the sensitization rates of patients in 2002 to those in 2007. METHODS: Two hundred fifty-eight patients with atopic dermatitis who visited Dong-A University Medical Center in 2002 (n=121) and 2007 (n=137) were enrolled in this study. Medical records were retrospectively reviewed to determine serum total eosinophil count (TEC), and total IgE and specific IgE to CM, EW, and soybean. RESULTS: The TEC was significantly higher in 2002 than in 2007. The sensitization rates to CM, EW and soy bean were significantly different in 2002 and 2007.(P=0.001 and P=0.03 for each) The sensitization rates to CM were significantly different according to age in 2007.(P= 0.04) The sensitization rates to EW were significantly different according to age in 2002 and 2007.(P=0.02 and P=0.00 for each) The sensitization rates to CM were significantly different according to combined allergic diseases in 2002 and 2007.(P=0.04, P=0.01 for each) The sensitization rates to EW were significantly different according to combined allergic diseases in 2002 and 2007.(P=0.00, P=0.002 for each) CONCLUSION: Among atopic dermatitis patients who visited a single university hospital in Busan, there were no significant differences in the overall sensitization rates in 2002 and 2007.


Subject(s)
Humans , Academic Medical Centers , Dermatitis, Atopic , Egg White , Eosinophils , Food Hypersensitivity , Immunoglobulin E , Incidence , Medical Records , Milk , Ovum , Retrospective Studies , Glycine max
2.
Journal of Korean Society of Pediatric Endocrinology ; : 100-103, 2008.
Article in Korean | WPRIM | ID: wpr-189897

ABSTRACT

Aplasia cutis congenita is a rare congenital anomaly characterized by focal absence of skin at birth. It most commonly manifests as a solitary defect on the scalp, but sometimes it may occur as multiple lesions. Frieden classified aplasia cutis congenita into nine types according to the associated anomalies, but a unifying theory has not been identified to explain the etiology of this disease. We report a case of a newborn with isolated aplasia cutis congenita on the scalp at birth, whose mother was treated with methimazole up to the 22 weeks of gestation due to hyperthyroidism.


Subject(s)
Humans , Infant, Newborn , Pregnancy , Ectodermal Dysplasia , Hyperthyroidism , Methimazole , Mothers , Parturition , Scalp , Skin
3.
Korean Journal of Pediatrics ; : 987-994, 2007.
Article in Korean | WPRIM | ID: wpr-128441

ABSTRACT

PURPOSE: This study investigated the clinical significance of AN in children and adolescents with obesity induced metabolic complications. METHODS: Forty-nine patients who had obesity induced metabolic complications were participated in this cross-sectional study. Obesity induced metabolic complications are as follows: hypertension, dyslipidemia, impaired fasting glucose (IFG), impaired glucose tolerance (IGT), nonalcoholic steatohepatitis (NASH), homeostasis model assessment of insulin resistance (HOMA-IR)>3.16. Clinical characteristics, such as, age, percentage-weight-for-height (PWH), pubertal status, blood pressure (BP), fasting plasma insulin level, fasting and post-oral glucose tolerance test 2-hour glucose levels, liver function test, lipid profile, HOMA-IR were compared according to the presence of AN. RESULTS: Sixty-five percent of patients had AN, 57.1% NASH, 57.1% dyslipidemia, 55.1% hypertension, 46.9% IFG, 24.5% HOMA-IR>3.16 and 16.2% IGT. The patients who were moderately to severely obese with AN had higher incidence of IGT and HOMA-IR>3.16. The patients with AN had significantly higher diastolic BP (79.4+/-6.9 vs 75.4+/-5.6 mmHg), fasting levels of plasma insulin (10.6+/-6.0 vs 6.2+/-5.4 microIU/mL), HOMA-IR index (2.6+/-1.4 vs 1.4+/-1.3) and PWH (42.4+/-13.0 vs 34.3+/-1.8%). The increasing tendency for the presence of AN was significantly related to the cumulative number of obesity induced metabolic complications. Binary logistic regression analysis revealed that the presence of AN was significantly associated with fasting plasma insulin level, PWH and IFG. CONCLUSION: AN could be useful as a clinical surrogate of obesity induced metabolic complications.


Subject(s)
Adolescent , Child , Humans , Acanthosis Nigricans , Blood Pressure , Cross-Sectional Studies , Dyslipidemias , Fasting , Fatty Liver , Glucose , Glucose Tolerance Test , Homeostasis , Hypertension , Incidence , Insulin , Insulin Resistance , Liver Function Tests , Logistic Models , Obesity , Plasma
SELECTION OF CITATIONS
SEARCH DETAIL