Evaluation of antimicrobial resistance of Acinetobacter baumannii to imipenem, ciporofloxacin and ceftazidime using E test

Resistance patterns among nosocomial bacterial pathogens in hospitals may vary widely from country to country at any given point and within the same country over time. Acinetobacter baumannii is one of the most important bacterium causes hospital acquired infections. Therefore, surveillance of antibiotic resistance of A. baumannii is necessary, especially in our country which there is no have much data in this field. In a prospective study, strain comprised of a total of 191 recent clinical isolates selected consecutively from clinical infections of separate patients from three University hospitals in Tehran. Minimum inhibitory concentration [MIC] of these organisms for imipenem, ciprofloxacin and ceftazidime was determined using E test method according to CLSI guideline. Also, MIC50 and MIC90 percent was calculated for each of these antibiotics. The percentages of Acinetobacter baumannii isolates susceptible to ciprofloxacin and ceftazidime by E test were 55.5% and 44.5%, respectively. The percentage of bacterium susceptible to imipenem by E test was 72.8%. MIC50 and MIC90 of imipenem in E test were 1.5 and > 32, respectively. High antimicrobial resistance against A. baumannii species has been seen in Iran; therefore, it is necessary to implement some approaches for prevention of bacterial spread

[Clinical manifestations of extra pulmonary tuberculosis in Loghman-Hakim hospital]

About one- third of patients of tuberculosis have extra pulmonary involvement. In previous studies the most frequent sites of involvement have been reported lymph nodes, pleura, urogenital tract, skeletal system, meanings and peritoneum, respectively. A descriptive study was performed on 81 patients with pathology report of extra pulmonary tuberculosis, admitted to Loghman- Hakim hospital, from 1375 to 1380. 48% [30] were male. The mean age was 35 +/- t19.4 years. The mean age of male patients was 37.5 +/- t21.2 years and that of female patients was 31.1 +/- t16.83 years. 82.8% [67] were Iranian and 17.2% [14] were Afghan. In this study; 29 cases [35.8%] had tuberculosis lymphadenitis, 14 cases [17.2%] had tuberculous peritonitis, 12 cases [14.8%] had Skeletal tuberculosis, 6 cases [7.4%] had hepatic tuberculosis, 5 cases [6.1%] had Pleural tuberculosis, 4cases [4.9%] had cutaneous tuberculosis, 4 cases [4.9%] had tuberculosis synovitis, 2 cases [2.46%] Omentum tuberculosis, one case [1.2%] had tuberculosis parotitis, one case [1.2%] had chest wall tuberculosis, one case [1.2%] tuberculosis meningitis, one case [1.2%] had ovary tuberculosis, and one case [1.2%] had uterus tuberculos is. Considering the long course of the illness before admission and because of different primary diagnoses made on patients with extra pulmonary tuberculosis, this disease must be considered in differential diagnosis of every patient