ABSTRACT
Preeclampsia is a disorder of pregnancy with increased maternal and fetal morbidity and mortality. Endothelial cell dysfunction is important in the pathogenesis of preeclampsia. An imbalance between free radical induced lipid preoxidation and antioxidant system such as ceruloplasmin has been suggested as a possible pathogenic factor in preeclampsia and disturbing endothelial function. The aim of this study is to compare serum ceruloplasmin level in preeclampsia and normal pregnancy. This is a cross-sectional study that was performed on 39 preeclamptic patients [21 mild and 18 severe preeclampsia as case group] and 30 women with normal pregnancy [control group]. Five cc of blood was obtained from each patient and serum ceroloplasmin level was measured with special kit. Data were analyzed by one-way ANOVA Kruskal-wallis tests and ROC curve. P<0.05 was considered statistically significant. Maternal serum ceroloplasmin level was significantly different between the studied groups [P=0.47]. Increased serum ceroloplasmin level can be used as a predictive factor to diagnose severe preeclampsia
Subject(s)
Humans , Male , Female , Pregnancy , Pre-Eclampsia , Cross-Sectional Studies , Pregnancy ComplicationsABSTRACT
Today use of chelater materials such as RC Prep for easy root canal preparation with rotary instruments has been increased. According to the importance of apical seal and probably influence of instruments and materials on apical constriction size, the aim of this study was to evaluate the effect of RC Prep on apical leakage. In this experimental invitro study the crown of 66 single-root extracted human adult teeth with minimum root curve and same diameter were resected and divided to 3 experimental groups and two control groups [test groups: 20 teeth, control groups: 3 teeth]. The working length determined 1mm from the apex. The canals were prepared as follow: Group A: The canals were prepared by step back technique [MAF#40] and RC Prep, irrigated by 5cc Naocl2.6% and obturated by AH26 and gutta percha via lateral condensation. Group B: The canals were prepared and obturated similar to group A without use of RC Prep. Group C: The canals were prepared like group A, but the irrigator was saline. Root canals of control groups were prepared like group A, but the canals of group D [positive control] were not obturated. Crowns of experimental groups and negative group were sealed by glass Ionomer. Then the surface of all roots except 2mm of apical end were covered by nail polish. Teeth were incubated in 37°C and 100% humidity for 24 hours, then centrifuged in India ink for 15 minute by 3000 rpm and soaked in it for 72 hours. They were mounted in polyster and sectioned buccolingually. The dye penetration was measured by stereomicroscope with 0.1mm accuracy. The data analyzed by ANOVA and DUNCAN test. The results showed that there was a statistical difference between exprimental groups [P=0.011]. This difference was between groups B and C [P=0.008] and leakage was lower in group C. Groups A and B, A and C did not have significant differences, statistically. RC-Prep as a lubricant and chelator doesn't have any effect on apical leakage and is useful for canal preparation by instruments
ABSTRACT
The importance of determining working length in root canal therapy is clear for each clinician, and conventional radiography has been the technique of choice so far. But developing computerized technology in radiology and it's show up devices in the market, having several advantages, makes the tendency to use such technology more and more. Despite the many studies in this field, the accuracy of these devices is still unclear. The purpose of this study was to compare the accuracy of conventional radiography and digital radiography in order to estimate the working length of root canal. For this in experimental vitro study 17 root canals of maxillary and mandibular molar teeth on human skulls were selected. Size #15 files were placed in canals in order to assess working length. Then two radiography were taken from each canal: one using conventional and the other one using digital technique, through parallel method of radiation accomplished by special positioning devices. Next the teeth were extracted and real working length was determined. After that two independent observers estimated working length in both conventional and digital radiographs. Finally the mean working lengths of each group were compared with the real amounts using paired t-test analysis. In all tests a significance level of 0.05 was determined. Statistical analysis revealed that digital radiography was more accurate than conventional radiography in determining the working length [P=0.019]. Due to the greater accuracy and other advantages of digital radiography, this method is strongly recommended, regarding the similarities between the study and clinical situation for working length determination