ABSTRACT
In this survey, resistance to albendazole was investigated in 15 sheep flocks from different regions of Khozestan province. On each flock, two groups of 15 sheep including control groups [untreated] and Albendazole group [treated with 5 mg/kg of Albendazole] were selected and the investigation was carried out using faecal egg count reduction test[F.E.C.R.T] for 10 days after treatment. Posttreatment faecal culture and necropsy of 4 sheep from control group and 6 sheep from Albendazole group were done to identify species of resistant nematodes. Results of F.E.C.R.T showed that 27% of the flocks were resistant, 53% were suspected to resistancy and the rest were susceptable to albendazole. Faecal culture of necropsied animals showed that resistantce to albendazole was developed in Ostertagia circumcincta and Marshalagia marshali
Subject(s)
Animals , Drug Resistance , SheepABSTRACT
TTV was first isolated from the serum of a Japanese patient with post transfusion hepatitis of unknown etiology in 1977. TTV has been visualized by electron microscopy and was found to be an unenveloped, small, spherical particle with a diameter of 30-32 nm, and is a member of family related to Circovridae family. The exact role of TTV in the pathogenesis of liver disease is yet to be established. Our aim was to determine the prevalence of TTV in thalassemic patients in Ahwaz. Viral DNA was studied in 250 thalasemic patients. The results were compared with those of 250 blood donor controls. DNA was extracted from plasma and amplified by semi nested polymerase chain reaction with reported primer sets from a conserved region of the TTV genome. 57.2% [143/250] samples obtained from patients and 20% [54/250] of blood donors were positive for TTV-DNA detected by PCR. The difference in TTV prevalence between the two groups was statistically [CHI 2] significant [P= 0.0001]. The prevalence of TTV-DNA in Iranian thalassemic patients is high, which is the same as other countries