ABSTRACT
Hepatoid carcinoma is a primary malignant extrahepatic tumor that arises outside the liver and resembles hepatocellular carcinoma both histologically and immunohistochemically in its staining for alphafoetoprotein. It's a very rare tumor described in the ovary, the lung, the stomach, the kidney and the bladder. It is seen especially at the sixth decade. We report a case of a 73-years-old woman followed since 2008 for a poorly differentiated carcinoma of the left ovary treated surgically. In the absence of adjuvant therapy, she presented one year later, with a necrotic lomb-aortic mass and an increased level of CA125 [188 u/mm]. After three [3] courses of chemotherapy, the disease progressed rapidly with resumption of tumoral syndrome and bone metastases. The case was reviewed at our institution and implemented by an immunohistochemistry analysis. The diagnosis of hepatoid carcinoma of the ovary was therefore retained. This entity was first described by Ishikura and Scull in 1987. hepatoid carcinoma was reported 18 times in the ovary. The clinical and radiological signs are not specific. Biology can guide diagnosis with elevated serum AFP. The diagnosis is pathological. The differential diagnosis include ovarian metastasis of hepatocellular carcinoma and hepatoid yolk sac tumor. Differentiating the tumor is primordial and critical, because treatment modalities depend on the exact nature of the hepatoid cancer