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1.
Maroc Medical. 2011; 33 (1): 17-20
in French | IMEMR | ID: emr-146029

ABSTRACT

Basal cell carcinoma is a rare tumor mainly affecting major salivary glands, it's a low grade malignancy with cytological features of a basal cell adenoma but whose evolution indicates malignancy. We report the case of a 30 years old woman, who presented two years ago with a right parotid swelling gradually increasing. The computed tomographies [CT] show an ulcerative infiltrating tumor in the parotid gland extending locoregional lymph nodes. The evolution was marked by ulceration of the skin overlying the cervical lymph node with magma. The diagnosis was made on biopsy sample using morphological study, immunohistochemistry and radiological data. This tumor presents problems of differential diagnosis mainly with basal cell adenoma of the parotid gland. The high number of mitoses and infiltrative character on CT allowed to retain that diagnosis. Surgical treatment is sometimes coupled with adjuvant radiotherapy. The evolution is marked by frequent recurrences with rare metastasis. Basal cell carcinoma is usually of good prognosis and its diagnosis is histopathological


Subject(s)
Humans , Female , Parotid Neoplasms/pathology , Neoplasm Metastasis , Immunohistochemistry , Diagnosis, Differential , Skin Neoplasms
2.
Maroc Medical. 2011; 33 (2): 101-104
in French | IMEMR | ID: emr-146039

ABSTRACT

Mammary hamartomas are uncommon benign lesions. The reported incidence of breast hamartomas is 0.7% of benign breast tumors in female. In this paper, we report a case of breast hamartoma emphasizing the role of the pathologist in remaining this diagnosis. A 37 years old women, presented with a voluminous lump of the breast with mastodynia. On clinical examination, the lump was in the external quadrants of the right breast measuring 7 cm in the great diameter with no controlateral or axillary abnormalities. Ultrasound examination and mammography showed an ACR3 tissular heterogenic mass suggesting the diagnosis of phyllode tumor or hamartoma. On needle core biopsy the diagnosis was favor a mammary hamartoma associated to a proliferative mastopathy. The mass was excised and the histologic examination confirmed the initial diagnosis according to the clinico-radiologic context associated with mastosis. Epithelial changes and mastosis may be seen within the hamartoma and should be reported. On the other hand, although hamartomas are benign, coincidental malignancy can occur, thus, adequate sampling of mammary hamartoma is essential. Mammary hamartomas are uncommon benign lesions that are probably underestimated because of lacking of specific diagnostic criteria. Correlation with the imaging findings and clinical impression is necessary to retain this diagnosis. The treatment is surgical lumpectomy and the prognosis is good


Subject(s)
Humans , Female , Breast Diseases/pathology , Mammography , Mastectomy, Segmental , Biopsy
3.
Maroc Medical. 2010; 32 (4): 261-264
in French | IMEMR | ID: emr-133590

ABSTRACT

Adenoid cystic carcinoma is a malignant neoplasm described in the salivary glands. Primary adenoid cystic carcinoma of the cervix is extremely rare, accounting for less than 1% of all cervical carcinomas. A 54 years old woman presented with the complaints of vaginal bleeding and pain. The cervical examination revealed a polypoid swelling mass measuring 1.5 cm in great dimension. A cervical biopsy diagnosed an adenoid cystic carcinoma associated with cervical intraepithelial neoplasia grade III [CIN III]. After a brachytherapy, the patient went through a radical surgery. The pathological study of the specimen confirmed the initial diagnosis. Adenoid cystic carcinoma is more common in the salivary glands and respiratory tract glands. Exceptionally, it may arise in the cervix. An accurate diagnosis is exclusively established by pathology. The histological appearance is similar to its counterpart in salivary glands .the characteristic cystic spaces are filled with a slightly eosinophilic hyaline material or basophilic mucin and are surrounded by palisaded epithelial cells. The most important differential diagnosis of cervical adenoid cystic carcinoma is ademoid basal carcinoma which has a better prognosis. Adenoid cystic carcinoma of the cervix is an uncommon neoplasm. Histological examination is necessary to confirm this diagnosis. The optimal treatment combines surgery and radiotherapy associated to chemotherapy. The prognosis remains poor

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