ABSTRACT
Aloe vera [Aloe barbadensis M.] as a medicinal herb is practiced in wound healing. This study was carried out to assess the effect of Aloe vera gel [mucilage] on TGF- beta gene expression in incisional skin wound in BALB/c mice. In this experimental study, 36 BALB/c male mice with weight range 22 +/- 2 gr were allocated equally into negative control [no wound], sham-operated [wound treated with physiological serum] and teratment [wound treated with Aloe vera gel]. Two equal full-thickness skin wounds of 10 +/- 2mm were made on either side of the vertebral column in the sacral region. The animals in the teratment group were received daily, 2 gram of Aloe vera gel [without any bandage] as a thin layer for a period of 16 days. On 8th and 16th post wounding day, TGF- beta gene expression in incisional wounds and Malonyldialdehyde [as end-product of lipid peroxidation] in serum samples was measured using RT-PCR and spectrophotometry methods, respectively. TGF- beta gene expression in incisional skin wound increased in Aloe vera gel treated group in compared to negative control and sham-operated groups [P<0.05]. Malonyldialdehyde concentration was significantly reduced in Aloe vera treated group in comparision with negative control and sham-operated groups. Aloe vera gel can induce growth factor TGF- beta gene expression and reducing the lipid peroxidation content can play an important role in incisional skin wound healing process
ABSTRACT
Quality of life in post-menopausal women and menopausal symptoms are closely related concepts. Influence health education policy in order to promote health and adopt a menopause lifestyle requires alternative strategies, including health training programs with community - based interventions. The current study aims to survey the effects of support groups on quality of life of post-menopausal women. A blind field trial [2010] was conducted at Saadatmandii Clinical Center [Robat Karim, Iran]. 110 women were selected randomly divided into test and control groups [consisting of 55 ones]. Menopause specific quality of life questionnaire [MENQOL] was used for evaluation of life quality before and three months after intervention; there was no intervention in the control group. Data were analyzed by using SPSS/16. Qualitative variables were analyzed using chi-square tests and quantitative variables were analyzed using Mann-Whitney and Wilcoxon test, paired T-test and independent t-test. There was significant difference between vasomotor, psychosocial, physical, sexual aspects and life quality of this group pf women [P<0.001]. There was no statistically significant difference in the quality of life of women in control group. According to the results method of support group can lead to improved quality of life for postmenopausal ones and it can be appropriate healthcare policy to promote health and improve life quality of this group of women
ABSTRACT
Total seal in the root apex for healing of periodontium is an important goal of endodontic surgery that is obtained by application of various kinds of retrograde materials. The purpose of this study was to evaluate and compare marginal adaptation of two retrograde materials [Gray MTA and Portland cement], using SEM. In this invitro study, 50 extracted single-rooted human teeth with mature apices, without decay, absorption or root fracture were selected. The canals were instrumented by rotary system and filled with gutta-percha and then 3 mm of the root-end was resected. Then a cavity was prepared at the root-end with 3 mm depth and 1 mm width. Next, the teeth were divided into two groups of 25 teeth each. Each group was filled with one of the retrograde materials [Gray MTA or Portland cement]. After that, the teeth were resected longitudinally to create buccal and lingual sections. Finally, the gap was determined and recorded in millimeter in two dimensions. The data were analyzed using Mann-Whitney test and Fisher's Exact test. The mean gap in Gray MTA and Portland cement were 211.6micron and 326.3 micron, respectively. The difference was not statistically significant. There was no significant difference in marginal adaptation between Gray MTA and Portland cement
Subject(s)
Humans , Dental Cements , Aluminum Compounds , Oxides , Gutta-PerchaABSTRACT
Various kinds of hand-held or rotary techniques are used for mechanical preparation of the canal. The purpose of this study was to assess the influence of the number of applications on apical extrusion of debris in conventional and two rotary instrumentation techniques [Profile, Flex Master]. In this in vitro study, 75 extracted single-rooted human mandibular premolars with curvature between 0-10 degrees were selected and divided into three groups of 25 teeth each. All teeth were shortened to length of 15 mm by cutting the crown. Group H was prepared by hand step back technique, group P was prepared by profile system and group F was prepared by Flex Master system. The number of applications was according to manufacturer recommendation. For collection of debris, vials of distilled water were used that were weighed before preparation by 0.0001 weighing machine. At the end of canal preparation, vials were completely dried and weighed again. The difference between the weights of vials in two stages was the weight of debris extruded from apical foramen. The mean weight of debris in various numbers of applications within each system was compared by one-way variance analysis. Comparing the various numbers of applications in each system, it was noted that only in profile group, with increasing the number of applications, the quantity of debris extrusion was reduced. Unused profile instruments induce more extrusion of debris from apical foramen, rather than used ones