ABSTRACT
This prospective study attempted to determine the epidemiology, clinical manifestations and prognosis of patients with hospital and community-acquired bacteremia of Klebsiella pneumoniae. From July 1, 2004, to March 31, 2005, we prospectively studied 34 episodes of klebsiella pneumoniae bacteremia in 34 patients, treated in Imam Reza Hospital, Mashhad-IRAN. The disease was nosocomially acquired in 58.8% and community acquired in 41.2%. The different types of infection were sepsis [44.1%], burn wounds [26.5%], pneumonia [1 1.8%] endocarditis [2.9%], urinary tract infection [2.9%], and hepatic abscesses [2.9%]. Bum which was found in 9 [45%] patients, was the most common underlying disease, followed by renal failure in 3 [15%], Diabetes mellitus in 2 [10%], leukemia in 2 [10%], and intravenous drug abuse in 1 [5%]. The most frequent clinical findings in adult patients were fever [100%], leukocytosis [75%], thrombocytopenia [45%], jaundice [40%], cough [30%], tachycardia [30%], tachypnea [25%], rigors [25%], Hemoptysis [15%] and anemia [11.1%]. Carbenicillin and ciprofloxacin were the most active antibiotics. We observed that nosocomial infections are more prevalent than community aquired. Sepsis without focous, burn and neonatal infections were some of the most significant diseases in this study