ABSTRACT
Studies show that antioxidants are beneficial for male infertility. Considering that sesame seed contains several important antioxidants, this study was designed to examine the effect of a sesame seed regimen on the testicular structure and sex hormones in adult rats. This experimental study was conducted on 30 adult male Wistar rats [200 g] prepared from Physiology Research Center at Kashan University of Medical Sciences. Rats were randomly divided into the experimental and control groups. The control group received the standard regimen, while the experimental group received a special regimen [70% standard food+30% sesame seed] after weaning for 12 weeks. At the end of the study, the weight and volume of the testis and seminiferous tubules, the lumen epithelium diameter, LH, FSH and testosterone levels were evaluated. No significant difference was found between the two groups in body weight, the weight and volume of the testis and the volume percentage of vessels in seminiferous tubules, while the mean number and motility of sperms in epididymis, the number and volume percentage of epithelial cells, lumen and interstitial space as well as the diameters of the tubules were significantly different in the experimental compared to the control group [P<0.0001]. Moreover, there was a significant difference between the two groups in LH level [P=0.03]. Sesame seed intake improves the testicular parameters, fertility and sperm production in male rats
ABSTRACT
Background: Regarding the current trend of turning attention towards the clinical application of herbal drugs in the healing of burn wounds, the present study was designed to evaluate the effect of Arnebia leaf on the healing process of second degree burn wounds in rat
Materials and Methods: After the production of a second degree burn covering 10% of total body surface area on 40 adult albino rats [weighing 220+/-30 g.] animals were divided into 4 groups: treatment group using herbs containing Arnebia leaf; treatment group using herbs containing no Arnebia leaf; silver sulphadiazine [SSD] treatment group and normal saline treated group. All groups were treated and controlled once a day up to the 30[th] day that they decapitated for histological study of healing process [e.g. epidermal area density, blood vessel density and number in the area]. Data analyses were done using one-way ANOVA and post-hoc Tukey tests
Results: Morphometric studies showed that herbal treatment group containing Arnebia leaf compared to herbal treatment group with no Arnebia leaf and SSD group for epidermal area density had a significant lower [P<0.0001 and P<0.002, respectively] and compared to no Arnebia leaf group a significane higher number and density of blood vessels [P<0.001 and P=0.004, respectively]
Conclusion: This study shows that Arnebia leaf did not have any effect on healing of second degree burn wounds in rat's. More study were recommended for evaluating the effects of other parts of the plant on burn healing