ABSTRACT
Protozoa are among the most important pathogens that can cause infections in immunocompromised hosts. These microorganisms particularly infect individuals with impaired cellular immunity such as those with heart transplant patients using high doses of corticosteroids. The protozoa that most frequently cause disease in immunocompromised patient are, Toxoplasma gondii, Leishmania, Enterocytozoon bieneusi, Trypanosoma Cruzi, Babesia microtti and Plasmodium falciparum can cause acute meningoencephalitis, acute myocarditis, hepatospleenomegaly, pnemonia, chronic diarrhea and bone marrow, Lung, hepatic, spleen involvement. There are various, serological parasitological histological and molecular methods for the diagnosis of these infections. Owing to the increasing number of transplantation we expect increased occurrence of opportunistic infections. For this review article we have searched through the sites pubmed and google by the following keywords: protozoa, infection, heart transplant. We have found over 30 related article. In heart transplant recipient patient protozoan pathogen are terrible life thretening so it is important to take into consideration the use of choice drugs and preventive methods as earlier as possible
Subject(s)
Humans , Opportunistic Infections/diagnosis , Eukaryota , Heart Transplantation/mortality , Living Donors , Immunocompromised Host , Immunity, Cellular , Adrenal Cortex Hormones/adverse effects , Meningoencephalitis/etiology , Myocarditis/etiology , Hepatomegaly/etiology , Pneumonia/etiology , Splenomegaly/etiologyABSTRACT
Background: Protozoa are among the most important pathogens that can cause infections in immunocompromised hosts. These microorganisms particularly infect individuals with impaired cellular immunity such as those with heart transplant patients which using high doses of corticosteroids. The protozoa that most frequently cause disease in immunocompromised patient are, Toxoplasma gondii, Leishmania, Enterocytozoon bieneusi, Trypanosoma Cruzi , Babesia microtti and Plasmodium falciparum can cause acute meningoencephalitis, acute myocarditis, hepatospleenomegally, pnemonia, chronic diarrhea and bone marrow, Lung, hepatic, spleen involvement. There are various, serological parasitological histological and molecular methods for the diagnosis of these infection. Owing to the increasing number of transplantation we expect increase occurring opportunistic infections
Materials and Methods: For this review article we have searched through the sites pubmed and google by the following keywords: protozoa, infection, heart transplant. We have found over than 30 related article
Results and Conclusions: In heart transplant recipient patient protozoan pathogen are terrible life tretening so it is important to take into the consideration the using of choice drugs and preventive methods as earlier as possible