ABSTRACT
Helicobacter pylori is known as the most common causative agent of bacterial infection in human which causes peptic ulcer and gastric tumor To investigate the incidence of HP infection in different endoscopic lesions from125 patients in Qazvin Bouali Sina hospital. This was a descriptive study on endoscopic lesions of patients referred to Bouali Sina hospital in 2001-2002 [June- January]. The present study was an endoscopic-based observation in which the data collected through using a questionnaire, endoscopic finding andalso a biopsy from tantrum for rapid urea's test if the patient was suitable to be included in our study. The data was further statistically analyzed using SPSS. The incidence of H.P in duodenal ulcer was 70%. Other findings were: normal endoscopic appearance [58.8%], gastric ulcer [43.7%], erythema of antrum [62.2%] and esophagitis [40.7%]. Epigastric pain was the most common clinical manifestation among the first four groups whereas the hurt burn was the dominant complaint in esophagitis group. Following the administration of different treatment protocols against HP infection, the incidence of HP decreased in different gastrointestinal diseases