ABSTRACT
A programmed study on the effect of sodium thiopentone and midazolam on systemic blood pressure, pulse rate and intraocular pressure was done on sixty patients. A significant increase of all parameters was found after one minute. These values became less increased after three minutes. After five minutes a significant decrease of systolic and diastolic pressure, and intraocular pressure, as well normalization of pulse rate was found for both groups. A comparison between the results of both groups show that the systolic pressure was more significantly increased under the effects of midazolam than thiopentone. In contrast to this, pulse rate and intraocular pressure showed similar changes in both groups
Subject(s)
Pulse , Blood Pressure , Thiopental , MidazolamABSTRACT
The effects of midazolam in a dose of 2.0-0.25 mg/kg body weight followed by succinylcholine in a dose of 1-1.5 mg/kg body weight, were studied during the induction of anaesthesia in 30 patients undergoing non-ophthalmic surgery. There was an increase in the studied parameters one minute after induction. Values started to decline after three minutes, and five minutes after induction the systolic blood pressure and intraocular pressure were both well below their initial values