ABSTRACT
Background and Objective: Nonalcoholic fatty liver disease is the most common cause of liver disease worldwide and it is defined as a disorder of excess fat accumulation in the liver. This study | was done to determine the prevalence of fatty liver among overweight, obese and normal children
Methods: This historical cohort study was conducted on 90 children ages 5 to 13 years old in Taleghani pediatric theching hospital in Gorgan, north of Iran during 2014. Subjects according to Body Mass Index [BMI] classified into obese [95%>BMI], over weight [85-95% BMI] and normal [5-85% BMI]. Childern were matched for age and sex. Liver enzymes [ALT Alanine aminotransferase and AST [Aspartate aminotransferase] and lipid profile includingTriglyceride: TG [High Density Lipoprotein: HDL and [Low Density Lipoprotein: LDL were measured and fatty liver evaluated based on sonographic parameters by a radiologist who didnot know children's BMI
Results: The prevalence of fatty liver was 23.3% in obese children that was non- significantly higher j than normal [16.7%] and over weight [16.7%] children. The prevalence of fatty liver was not] significantly different between two sexes. AST was significantly higher in children with normal BMI j in compared to obese and over weight children [P<0.05]. The highest and lowest level of cholesterol J was seen in obese and normal children [P<0.05]
Conclusion: This study showed that the prevalence of fatty liver non-significantly was higher u] obese children in comparision with normal and over weight children