Pharmacological studies on some new pyrazolones

Some new synthesized pyrazolone derivatives were tested for their possible anti-inflammatory, analgesic, antipyretic and ulcerogenic action. Compounds [II] 3-[p-chlorophenoxy]-1, 2-di phenyl-3- pyrazolin-5-one and [III] 3-[2, 4-dichlorophenoxy]-1, 2-diphenyl-3- pyrazolin-5-one showed a significant anti-inflammatory and antipyretic effects. Tested compounds failed to demonstrate any significant analgesic effect while they were all ulcerogenic