study on the preparation of certain 2-hydroxy-3-nitro-N,N,N-triemthylanilinium salts

Quaternization of 2-amino-6-nitrophenol, was successfully achieved after different attempts. Nitration of N, N, N- trimethylanilinium-2-oxide, afforded the 5-nitro derivative only. The anilinium oxides were prepared by anion or cation exchanging of the iodides on amberilite resins, IR 400 and IR 120, respectively

Synthesis and mass spectrometry of some a-dialkyla-minoalkylphenol structurally related to certain antiparasitic agents

The preparation of two groups of compounds each incorporating the a- dialkylaminoalkyl phenol residue of the well known antiparasitic activity, has been achieved and their behavior under electron-impact has been investigated

Synthesis of certain benzimidazole derivatives structurally related to antituberculous agents

Incorporation of an acid hydrazide, N2 substituted acid hydrazide or N4 substituted sulphonamide residues into a benzamidazole residue in a way fulfilling the required pattern for antituberculous activity in most antituberculous agents, with special reference to the highly potent isonicotinic acid hydrazide, has been achieved. This was verified via a 4-aminobenzoic acid or 4-aminobenzenesulphonamide link, which might create a type of competition between 4-aminobenzoic acid as a bacterial metabolite and the group of compounds