ABSTRACT
Reducing pain and enhancement of wound healing have several advantages. Wound healing is a complicated but regular process that includes synchronized and organized phenomena such as parenchymal cells migration, proliferation and synthesis of extra- cellular matrix proteins. Rate of wound healing is affected by various factors. The aim of our research was to study the effects of low power He-Ne laser radiation [632.8 nm] on metabolic process, cell proliferation and finally wound repairment. In our research about 50 healthy mature rats were studied by case-control method. After shaving, small cuts 10 mm in length were made at the neck. Then they were divided randomly into control and case groups. The rats of the case group were radiated by He-Ne laser to their wounds about four minutes each day. After a weak we did wound biopsy of both groups and all the specimens were studied microscopically. The data was analyzed by t-test. Findings showed that there were significant increase in the fibroblast and connective tissue fibers and also vascularisation in the case group compared with the control group. Wound healing in the case group was accelerated and wound diameter was smaller significantly. So low power He-Ne laser radiation accelerates wound healing process