Simple partial status epilepticus presenting with jargon aphasia and focal hyperperfusion demonstrated by ictal pulsed arterial spin labeling MRI

@#We report a case of 74-year-old lady, presented with recurrent jargon aphasia as simple partial status epilepticus (SPSE) which lasted for a few days to a few weeks, following a brain abscess removal from the left temporo-parieto-occipital region at the age of 71 years. The ictal activity on electroencephalogram was documented at left posterior quadrant, where marked hyperperfusion was clearly visualized by perfusion image acquired with magnetic resonance imaging (MRI) using pulsed arterial spin-labeling (PASL). Jargon aphasia as a primary feature of simple partial status epilepticus is so uncommon that only few cases have been reported. Furthermore, this report suggests that MRI using PASL is a promising method not only to localize the seizure foci but also to follow up the corresponding regional cerebral blood flow changes noninvasively.

The change of event-related potentials with choice task / 体力科学

Event-related potentials (ERPs) were recorded from 9 normal subjects engaged in a somatosensory target discrimination task. Subjects were instructed (1) to keep a mental count of each target or (2) to rotate a grip in the direction of abduction after each target stimulus using the right hand. Target stimuli were electrical pulses delivered randomly through ring electrodes to the left second digit with probabilities of 0.2, and nontarget stimuli were delivered to the left fifth digit with probabilities of 0.8.<BR>P 100 was prominent in somatosensory tasks, and had a widespread distribution on the scalp without having any relation to kinds of tasks, therefore, P 100 reflects the sensation of somatosensory stimulation. N 140 was largest at Fz in both counting and movement tasks, so our result supported the hypothesis that N 140 is generated in the frontal lobes regions. Moreover, N 140 latency was shorter during movement than during counting. These results indicate that N 140 is related to carrying out movement. P 300 was largest at Cz during counting, and largest at Pz and C4' during movement. These results also indicate that P 300 may have multiple intracerebral generators since P300 origin differs based on the kind of tasks or stimuli. In addition, the appearance of P300 after nontarget stimuli indicates that P 300 reflects a non-selective postdecision closure of cognitive activity. In conclusion, each component of ERPs may have a specific origin and specific characteristics.