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1.
Pakistan Journal of Medical Sciences. 2016; 32 (3): 555-558
in English | IMEMR | ID: emr-182940

ABSTRACT

Objectives: To analyze the comparison between the treatment area of 15Gage internally cooled electrodes and 17 Gage Cool Wet-tip[CWT] electrodes. They are manufactured to broaden treatment area of the tumor in the radiofrequency ablation of hepatocellular carcinoma[HCC]


Methods: The study was designed for 62 patients with a mean age of 61, ranging from 44 to 87 years. The sample comprised of patients who used 15 G internally cooled electrodes and 17 G CWT electrodes respectively. Computed tomography [CT] images obtained after the procedure were observed, however, for the ablation lesion, the volume was determined by measuring complete necrotic tissue that did not contrast enhancement in the image


Results: The treatment area of the tumor after radiofrequency ablation was 17.26 +/- 6.02 in the CWT, which was bigger than 15G. The treatment area ratio of the treatment before or after was significant at 581.85 +/- 339.56 in the CWT. After radiofrequency ablation, the treatment area got bigger, as 15G electrodes went toward CWT electrodes. Treatment area per electrode was 1.34 times higher in CWT than in 15G while the treatment area ratio of the treatment before or after was 1.001 times higher in the CWT than 15G


Conclusions: Ablation is more common for the safety margin in stable tumor and CWT type electrodes that can make larger ablation to reduce the number of times ablation is required for residual tumor and it decreases recurrence, ablation time and reoperation. Therefore it is considered t useful to reduce patients' pain

2.
Pakistan Journal of Medical Sciences. 2015; 31 (1): 31-36
in English | IMEMR | ID: emr-154968

ABSTRACT

The aim of this study was to investigate the difference of liver function changes according to the liver regeneration rate after liver transplantation through blood tests. Fifty donors, who underwent computed tomography [CT] 3D volumetry, were analyzed before and after liver transplantation. CT 3D volumetry was used as a study method to measure the mean liver regeneration volume and regeneration rate. Then, blood levels were measured including alanine transaminase [ALT], aminotransferase [AST], gamma-glutamyl transpeptidase [GGT] and total bilirubin. The liver regeneration rate rapidly increased from 39.13 +/- 4.91% befoone1 month and 90.31 +/- 13.09% 16 months after surgery furthermore. Blood levels rapidly increased 7 days after surgery and then decreased 16 months after surgery compared to the state before surgery. This study results could be used as a basis for the prognosis of future liver transplantations

3.
Pakistan Journal of Medical Sciences. 2015; 31 (5): 1043-1046
in English | IMEMR | ID: emr-174083

ABSTRACT

The purpose of this study was to find the correlations between biochemical study and liver cirrhosis. The patients had liver biopsy to check the degree of their liver fibrosis, from August 2013 to August 2014 at the current medical center. In order to find the etiology of hepatitis, a research was done on gender, age, weight, and biochemical study through the investigation of subjects' medical record and medical history. For biochemical study, we examined hemoglobin, platelets, albumin, aspartate aminotransferase [AST], alanine aminotransferase [ALT], total bilirubin, gamma-glutamyl transferase [GOT], prothrombin time [PT], and international normalised ratio [INR]. We also analyzed the factors that are related to liver cirrhosis. As a result, the patients at liver cirrhosis F>2 stage showed 0.973, which is higher than the patients at FO stage with 0.943. F>2 stage of hemoglobin was 0.544, which is lower than FO stage of hemoglobin with 0.817. Platelet count in F>2 stage was 0.417, which is higher than FO stage with 0.074. For Albumin, F>2 stage was 0.155 when FO stage was 0.135. ATS's F>2 stage was 0.665, which is 6 times higher than FO stage with 0.100. Moreover, in the case of GGT, F>2 stage was higher with 0.492 than FO stage with 0.078. In conclusion, it was confirmed that there is an increase in liver cirrhosis in the following general characteristics and biochemical factors: increase of age, increase of GGT, decrease of albumin, increase of the total bilirubin, and growth of INR [International Normalized Ratio]

4.
Pakistan Journal of Medical Sciences. 2015; 31 (5): 1207-1212
in English | IMEMR | ID: emr-174115

ABSTRACT

To study about the blood count of a risk factor related to physical measurement and metabolic syndrome, and the area of epicardial fat for medical checkup patients. From April 1[st]t to November 15[th] in 2014, we measured the area of epicardial fat in the adult out patients under 60 years of age, who are in good health; and the patients took the blood test and low-dose lung CT. In order to identify the relationship between the area of epicardial fat and the risk factor of metabolic syndrome, we conducted correlation analysis. Then, we performed multiple regression analysis to evaluate an independent correlation of epicardial area. In addition, we computed the cut-off value of epicardial fat area by using ROC [Receiver Operating Characteristic curve to foresee a metabolic syndrome factor that has the most proper sensitivity and specificity. aist circumference, fasting blood sugar, triglyceride, high-density lipoprotein [HDL] cholesterol, systolic blood pressure, and diastolic blood pressure were shown to be the factors that affect the area of epicardial fat. Therefore, if waist circumference, fasting blood sugar, triglyceride, systolic blood pressure, and diastolic blood pressure were increased, the area of epicardial fat would be significantly increased [P<0.05]; and if high-density lipoprotein cholesterol was increased, the area of epicardial fat would be significantly decreased [P<0.05]. Out of metabolic syndrome factors, waist circumference's ROC curve area was 0.79 [Confidence Interval 0.73-0.84, P<0.05], which was the highest. The sensitivity was 83.7% when specificity was 70.1%, which proves that they are important factors for the diagnosis. In brief, metabolic syndrome is a disease that mostly appears in obesity patients, so we should try to monitor and cure the disease. The risk factors of metabolic syndrome can be managed through health care, and if we try to decrease the risk factors, we will be able to shrink epicardial fat area and decrease metabolic syndrome at the same time

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