ABSTRACT
Insertion of intravascular catheters may be the most common procedure in neonatal intensive care units. One of these kinds of catheters, umbilical venous catheter is generally used for the small and sick neonates. But the indwelling umbilical venous catheter can cause many complications. The most common complication is thrombus formation in the lumen of the catheter. Neonatal thrombosis has symptomatic or asymptomatic clinical manifestations, which may have serious complications in case of intracardiac thrombosis. In our experience, the infant who has no symptom of thrombosis was treated with low dose aspirin and warfarin for right atrium thrombosis caused by umbilical venous catheterization. So, we report a case of right atrium thrombosis following umbilical catheterization in neonatal intensive care units.
Subject(s)
Humans , Infant , Infant, Newborn , Aspirin , Catheterization , Catheters , Heart Atria , Intensive Care Units, Neonatal , Thrombosis , WarfarinABSTRACT
BACKGROUND AND OBJECTIVES: The prevalence of Kawasaki myocarditis in the acute phase is thought to be nearly 100%, and its detection may be helpful to the early diagnosis of Kawasaki disease. This study was performed to survey echocardiographic functional study items, effective for the differentiation of Kawasaki myocarditis patients from normal children. SUBJECTS AND METHODS: We studied 18 children treated at our hospital between Feb 2001 and Jul 2001. Nine typical Kawasaki patients (patient group) and 9 normal children (control group) are included. RESULTS: The male to female ratio of the respective groups were 6:3 (patients group), and 4:5 (control group). The mean ages (2.4+/-1.3 years vs. 3.4+/-2.1 years) and mean body weights (14.4+/-3.7 kg vs. 15.7+/-6.6 kg) did not differ significantly between two groups. The mean values of propagation velocity (Vp) via left ventricular inflow Color M-mode Doppler were significantly different between the two groups (51.8+/-14.6 cm/sec in patients group vs. 66.4+/-9.1 cm/sec in control group, p=0.0304). No other echocardiographic functional values were significantly different across the two groups. In the patients group, seven children (77.8%) had carditis-suggesting 2D-echocardiographic findings (dilated left ventricle, pericardial effusion, mitral regurgitation) and/or abnormally decreased Vp (<55 cm/sec). CONCLUSION: We verified the mean difference of Vp between Kawasaki patients and normal children. Additionally, the detection rate of Kawasaki myocarditis in the acute phase appears to be increased through the adding of Vp values to 2D-echocardiogram results.
Subject(s)
Child , Female , Humans , Male , Body Weight , Early Diagnosis , Echocardiography , Heart Ventricles , Mucocutaneous Lymph Node Syndrome , Myocarditis , Pericardial Effusion , PrevalenceABSTRACT
Annular pancreas is a rarely found gastrointestinal tract malformation, and is frequently associated with Down syndrome. Endocardial cushion defect is a type of congenital heart disease, commonly also related to Down syndrome. However, a combination of endocardial cushion defect with annular pancreas has not been reported previously. We recently experienced such a case in 2 month old boy. Moreover Down syndrome was excluded through physical examination and a chromosomal study. We think it difficult to obtain a complete explanation for this condition through the currently known pathogenesis of annular pancreas and endocardial cushion defect.
Subject(s)
Humans , Infant , Male , Down Syndrome , Endocardial Cushion Defects , Endocardial Cushions , Gastrointestinal Tract , Heart Defects, Congenital , Pancreas , Physical ExaminationABSTRACT
No abstract available.
Subject(s)
Lung Neoplasms , Lung , Proliferating Cell Nuclear AntigenABSTRACT
We have seen a case of Edward syndrome in a new born neonate who was born at local obstetrics clinics to a healthy 27 years old mother. Just after birth, she was transfered to us and brought to emergency room, because of dyspnea and abnormal apperance, characterized by prominent occiput low set malformed ear, micrognathia, webbed neck, short sternum, small hip and bilaterally abducted index and 3rd fingers flexed upon with semian lines. She also had small sized great toes with mild dorsiflex bilaterally. There was cardiomegaly as shown on chest AP and EKG, as well as a Grade III/IV systolic murmmer on auscultation. There was however, no specific bnormalities on IVP. Chromosomal studies showed the presence of third chromosome in No. 18 chromosome resulting in a total of 47 chromosomes for this patient. A review of literature is made briefly.