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1.
Journal of Korean Biological Nursing Science ; : 1-8, 2016.
Article in Korean | WPRIM | ID: wpr-202744

ABSTRACT

PURPOSE: The purpose of this study was to explore the levels of stress, self-efficacy for smoking cessation, smoking temptation, and nicotine dependency, and to identify factors influencing nicotine dependency among male college students who smoke. METHODS: In this study, a cross-sectional survey design was adopted for 283 male college students who smoke in D city, Korea. Data was analyzed for descriptive statistics, Pearson's correlation, and multiple regression using the SPSS 20.0 program. RESULTS: The mean score of stress was 27.00+/-6.28, self-efficacy for smoking cessation was 25.61+/-6.71, smoking temptation was 53.87+/-11.02, and nicotine dependency was 3.63+/-1.96. There was a significant positive correlation between stress and nicotine dependency (r=.58, p<.001) and between smoking temptation and nicotine dependency (r=.59, p<.001). There was a significant negative correlation between self-efficacy for smoking cessation and nicotine dependency (r=-.59, p<.001). The significant factors influencing nicotine dependency were stress (beta=.357, p<.001), self-efficacy for smoking cessation (beta=.359, p<.001), and smoking temptation (beta=.297, p<.001). This model explained 60.3% of variance in nicotine dependency (F=105.59, p<.001). CONCLUSION: The results suggest that an intervention program is needed to reduce the perception of stress and smoking temptation, and to increase the ability of self-efficacy for smoking cessation among male college students who smoke with the intention to quit smoking.


Subject(s)
Humans , Male , Cross-Sectional Studies , Intention , Korea , Nicotine , Smoke , Smoking Cessation , Smoking
2.
Journal of Korean Biological Nursing Science ; : 69-77, 2016.
Article in Korean | WPRIM | ID: wpr-198609

ABSTRACT

PURPOSE: This study aimed to investigate the effects of a secondary stroke prevention education program on the health risk indicators and self-care compliance of stroke patients. METHODS: A non-equivalent control group pretest-posttest design was used to select the participants. Subjects were 54 stroke patients (27 in the experimental group and 27 in the control group) hospitalized in a K university hospital in D city, Korea. Health risk indicators and self-care compliance were measured both for a baseline, as well as after intervention. The data was analyzed using a chi-square test, paired t-test and ANCOVA. RESULTS: There were significant differences in systolic blood pressure, diastolic blood pressure, fasting blood sugar, weight and self-care compliance. CONCLUSION: The results of the study indicate that an educational secondary stroke prevention program is effective for health risk indicators and self-care compliance of patients. Therefore it can be used as an effective nursing intervention in clinical practice.


Subject(s)
Humans , Blood Glucose , Blood Pressure , Compliance , Education , Fasting , Korea , Nursing , Secondary Prevention , Self Care , Stroke
3.
Journal of Korean Biological Nursing Science ; : 213-220, 2016.
Article in Korean | WPRIM | ID: wpr-169683

ABSTRACT

PURPOSE: The aim of this study was to identify the influence of knowledge, attitude and preventive health behavior of cancer on nicotine dependency in male college students who have a habit of smoking. METHODS: In this study, a cross-sectional survey design was adopted for the 254 male college students who smoke in D and S city. The data was analyzed for descriptive statistics, t-test, Pearson's correlation coefficient and multiple regression analysis using the SPSS 20.0 program. RESULTS: Knowledge about lung cancer (β=-.407, p<.001), preventive health behaviors about cancer (β=-.223, p<.001) and the smoking period (5years≤) (β=.198, p=.001) were identified as the factors influencing nicotine dependency of the subjects. The model explained 33% of variance in nicotine dependency (F=20.49, p<.001). CONCLUSION: The results suggest that anti-smoking educators should include the strategies to increase knowledge about lung cancer and preventive health behaviors of cancer, and to reduce the smoking period in their smoking cessation program.


Subject(s)
Humans , Male , Cross-Sectional Studies , Health Behavior , Lung Neoplasms , Lung , Nicotine , Smoke , Smoking Cessation , Smoking
4.
Journal of Korean Biological Nursing Science ; : 132-139, 2015.
Article in Korean | WPRIM | ID: wpr-201212

ABSTRACT

PURPOSE: The purpose of this study was to verify the correlation analysis between fluid intake on skin hydration and pH of college students. METHODS: The subjects were 129 female nursing students in D city. Data were collected by a self-administered questionnaire, using a skin moisture checker and skin pH meter on faces, hands, and feet. The collected data were analyzed by descriptive statistics, t-test, ANOVA, and Pearson correlation analysis, using SPSS WIN, 20. RESULTS: The daily fluid intake was composed of 57% pure water, 21% caffeinated beverages, 22% non-caffeinated beverages. There were significant differences in average skin hydration on the three body parts according to pure water, caffeinated beverages, and non-caffeinated beverages; however, there was no significant difference measured by fluid intake. There was a significant positive correlation between fluid intake and skin hydration: between pure water and skin hydration. There was significant negative correlation between caffeinated beverages and skin hydration: between non-caffeinated beverages and skin hydration. CONCLUSION: The results suggest that fluid intake, pure water, caffeinated beverages, and non-caffeinated beverages have an effect on skin hydration and pH. Therefore, it is good to increase the amount of fluid intake but, it is recommended to increase the amount of intake of pure water rather than beverages to improve skin status.


Subject(s)
Female , Humans , Beverages , Drinking Water , Foot , Hand , Human Body , Hydrogen-Ion Concentration , Skin , Students, Nursing , Water
5.
Journal of Korean Biological Nursing Science ; : 150-158, 2015.
Article in Korean | WPRIM | ID: wpr-201210

ABSTRACT

PURPOSE: This study aimed to evaluate the effects of gargling with S-solution and gargling with A-solution on salivary pH, coated tongue, and dental plaque index in preschool children. METHODS: Non-equivalent control group pretest-posttest design was used to select the participants. 99 preschool children were divided into three groups. Dependent variables were recorded at baseline, 30 minutes, and 7 days after the first treatment was given. The data were analyzed using chi2-test, ANOVA, and repeated measures of ANOVA. RESULTS: There were no significant differences in dependent variables in pre-test. However, the salivary pH in the S-solution group had significantly increased after 30 minutes (p<.05) and then again 7 days (p<.01) after the first treatment. Also, the S-solution and A-solution groups had greater decrease in dental plaque index after 30 minutes and again 7 days after the first treatment (p<.001) than the control group. With respect to coated tongue, there were no significant differences among the three groups. CONCLUSION: The results of this study indicate that essential oil gargling after brushing is helpful in improving oral health due to auxiliary oral hygiene effects with natural products. Specifically, gargling with S-solution is more effective than A-solution on oral health in preschool children by neutralizing salivary pH and reducing dental plaque index.


Subject(s)
Child , Child, Preschool , Humans , Biological Products , Dental Plaque Index , Hydrogen-Ion Concentration , Oral Health , Oral Hygiene , Tongue
6.
Journal of Korean Biological Nursing Science ; : 188-210, 2015.
Article in Korean | WPRIM | ID: wpr-201206

ABSTRACT

PURPOSE: The purpose of this study was to develop syllabuses of basic nursing science subjects (Structure and Function of Human Body, Pathogenic Microbiology, Pathophysiology, and Mechanisms and Effects of Drug) based on learning outcomes. METHODS: We developed a 3-phase plan to develop the syllabuses. In the first phase, The Korean Society of Biological Nursing Science (KSBNS) held a workshop in May, 2013 in which professors who are in charge of basic nursing science subjects shared opinions about learning outcomes. As a result, initial prototype syllabuses came out. In the second phase, revised syllabuses based on learning outcomes were presented and discussed in the conference held by KSBNS in November, 2013. In the last phase, a research team who taught basic nursing science subjects finalized the syllabuses during the meetings. RESULTS: Syllabuses of 4 basic nursing science subjects were developed. CONCLUSION: These syllabuses of 4 subjects need to be disseminated throughout nursing colleges. Further revision needs to be made according to the circumstances and context of each school.


Subject(s)
Humans , Education , Human Body , Learning , Nursing
7.
Journal of Korean Biological Nursing Science ; : 19-27, 2015.
Article in Korean | WPRIM | ID: wpr-128556

ABSTRACT

PURPOSE: The aim of this study was to identify the effect of video programs of cardiopulmonary cerebral resuscitation (CPCR) education of cardiopulmonary cerebral resuscitation of nurses. METHODS: The subjects of the study were 64 nurses working in a university hospital. Nurse's CPCR performance have been measured four times (pre-test, post-test at immediately, 3 months and 6 months after intervention). Data were collected from February to August 2013. RESULTS: There were significant differences in knowledge, attitude, self-efficacy, and performance between groups by measure time. And there were significant interactions in knowledge, self-efficacy, and performance between groups, within groups, except for the attitude. The video programs of CPCR interventions appear to be effective in the improvement of knowledge, self-efficacy, and performance, as compared to the control group. CONCLUSION: The video programs of CPCR education was an effective intervention to improve and retain the level of knowledge, attitude, self-efficacy and performance. And the video program of CPCR education have an advantage of self-learning effect for nurses with shift work. Therefore video programs of CPCR education will be utilized for continuing nurse's education.


Subject(s)
Education , Resuscitation
8.
Journal of Korean Academy of Nursing ; : 221-230, 2015.
Article in Korean | WPRIM | ID: wpr-34128

ABSTRACT

PURPOSE: This study was done to examine how laughter therapy impacts serotonin levels, QOL and depression in middle-aged women and to perform a path analysis for verification of the effects. METHODS: A quasi-experimental study employing a nonequivalent control group and pre-post design was conducted. Participants were 64 middle-aged women (control=14 and experimental=50 in 3 groups according to level of depression). The intervention was conducted five times a week for a period of 2 weeks and the data analysis was conducted using repeated measures ANOVA, ANCOVA and LISREL. RESULTS: Results showed that pre serotonin and QOL in women with severe depression were the lowest. Serotonin in the experimental groups increased after the 10th intervention (p=.006) and the rise was the highest in the group with severe depression (p=.001). Depression in all groups decreased after the 5th intervention (p=.022) and the biggest decline was observed in group with severe depression (p=.007). QOL of the moderate and severe groups increased after the 10th intervention (p=.049), and the increase rate was highest in group with severe depression (p<.006). Path analysis revealed that laughter therapy did not directly affect depression, but its effect was indirectly meditated through serotonin variation (p<.001). CONCLUSION: Results indicate that serotonin activation through laughter therapy can help middle-aged women by lessening depression and providing important grounds for depression control.


Subject(s)
Adult , Female , Humans , Middle Aged , Depression/pathology , Laughter Therapy , Quality of Life , Serotonin/blood , Severity of Illness Index , Surveys and Questionnaires
9.
Journal of Korean Academy of Nursing ; : 552-562, 2014.
Article in Korean | WPRIM | ID: wpr-202155

ABSTRACT

PURPOSE: This study was done to identify the patterns and significant predictors influencing hospitalization of Korean men for alcohol use disorder. METHODS: A descriptive study design was utilized. Data were collected using self-report questionnaires from 143 inpatients who met the DSM-5 alcohol use disorder criteria and were receiving treatment and 157 social drinkers living in the community. The questionnaires included Alcohol Use Disorders Identification Test (AUDIT), Alcohol Problems, Alcohol Expectancy Questionnaire (AEQ), Life Position, and The Korean version of the Children of Alcoholics Screening Test (CAST-K). Data were analyzed using descriptive statistics, t-test, chi2-test, F-test, Pearson correlation coefficients, and logistic regression with forward stepwise. RESULTS: AUDIT had significant correlations with alcohol problems, alcohol expectancy, and parents' alcoholism. In logistic regression, factors significantly affecting hospitalization were divorced (OR=4.18, 95% CI: 1.28-13.71), graduation from elementary school (OR=28.50, 95% CI: 8.07-100.69), middle school (OR=6.66, 95% CI: 2.21-20.09), high school (OR=6.31, 95% CI: 2.59-15.36), drinking alone (OR=9.07, 95% CI: 1.78-46.17), family history of alcoholism (OR=2.41, 95% CI: 1.11-5.25), interpersonal relationship problems (OR=1.28, 95% CI:1.17-1.41), and sexual enhancement of alcohol expectancy (OR=0.83, 95% CI: 0.72-0.94), which accounted for 53% of the variance. CONCLUSION: Results suggest that interpersonal relationship programs and customized cognitive programs for social drinkers in the community are needed to decreased alcohol related hospitalization in Korean men.


Subject(s)
Adult , Aged , Humans , Male , Middle Aged , Alcohol-Related Disorders/diagnosis , Asian People , Divorce , Family Relations , Hospitalization , Interpersonal Relations , Logistic Models , Odds Ratio , Predictive Value of Tests , Surveys and Questionnaires , Republic of Korea
10.
Journal of Korean Academy of Nursing ; : 294-304, 2014.
Article in Korean | WPRIM | ID: wpr-175616

ABSTRACT

PURPOSE: The influence of dietary composition on blood pressure is an important subject in healthcare. Interactions between antihypertensive drugs and diet (IBADD) is the most important factor in the management of hypertension. It is therefore essential to support healthcare providers' decision making role in active and continuous interaction control in hypertension management. The aim of this study was to implement an ontology-based clinical decision support system (CDSS) for IBADD management (IBADDM). We considered the concepts of antihypertensive drugs and foods, and focused on the interchangeability between the database and the CDSS when providing tailored information. METHODS: An ontology-based CDSS for IBADDM was implemented in eight phases: (1) determining the domain and scope of ontology, (2) reviewing existing ontology, (3) extracting and defining the concepts, (4) assigning relationships between concepts, (5) creating a conceptual map with CmapTools, (6) selecting upper ontology, (7) formally representing the ontology with Protege (ver.4.3), (8) implementing an ontology-based CDSS as a JAVA prototype application. RESULTS: We extracted 5,926 concepts, 15 properties, and formally represented them using Protege. An ontology-based CDSS for IBADDM was implemented and the evaluation score was 4.60 out of 5. CONCLUSION: We endeavored to map functions of a CDSS and implement an ontology-based CDSS for IBADDM.


Subject(s)
Humans , Antihypertensive Agents/therapeutic use , Biological Ontologies , Databases, Factual , Decision Support Systems, Clinical , Diet , Drug Interactions , Hypertension/drug therapy , Software
11.
Korean Journal of Women Health Nursing ; : 248-256, 2012.
Article in Korean | WPRIM | ID: wpr-206197

ABSTRACT

PURPOSE: This study examines the difference of optimism, self-esteem and depression to verify an effect of laughter therapy program for menopausal women. METHODS: A quasi-experimental nonequivalent control group pre / post-test design was used. The participants (n=57) were 28 in the experimental group and 29 in the control group. The data were collected in December of 2011. The experimental group participated in laughter therapy for 30 min per session, five times a week for the period of 2 weeks. The questionnaires were used to measure pre / post-test optimism, self-esteem, and depression of menopausal women. RESULTS: The results showed that laughter therapy was effective in increasing optimism (p=.020) and self-esteem (p<.001). And the depression of menopausal women decreased (p=.003). CONCLUSION: The result of the study indicates that laughter therapy for menopausal women may be an effective nursing intervention to improve optimism, self-esteem and depression of menopausal women.


Subject(s)
Female , Humans , Depression , Laughter , Laughter Therapy , Menopause , Surveys and Questionnaires
12.
Journal of Korean Academy of Community Health Nursing ; : 512-521, 2010.
Article in Korean | WPRIM | ID: wpr-69557

ABSTRACT

PURPOSE: The remarkable progress in information and communication technology has had a great effect on the healthcare delivery system. The development of smart phone applications is a new field. The aim of our research was to provide assistance in developing smart phone applications for community health nursing. METHODS: Based on an informative approach, this study developed persona and site maps, followed by a storyboard as a way of analyzing users' requirements and designing responses in the context of smart phone application development methodology. RESULTS: We developed persona, user interface and database design successfully, and then seven nurses selected four nursing problems (income, residence, pain, and digestion hydration). The search time in seconds for the 2005 English OMAHA guidelines to find three nursing interventions for these problems was used to evaluate the effectiveness of the smart phone application. The results showed that smart phone applications' search was 21 times faster on the average than book guidelines. CONCLUSION: An English version of the OMAHA system application was developed for the Android smart phone market. It is hoped that smart phone applications such as this will be used internationally for nursing education.


Subject(s)
Community Health Nursing , Delivery of Health Care , Digestion , Education , Education, Nursing , Hope , Nursing , Nursing Informatics , Smartphone
13.
Healthcare Informatics Research ; : 15-21, 2010.
Article in English | WPRIM | ID: wpr-152074

ABSTRACT

OBJECTIVES: Reference values are highly required parameters for all tests in the clinical laboratory, and the supplementary provision of reliable reference intervals is an important task for both clinical laboratories and diagnostic test manufacturers. Despite the progress that has been made in the conceptual aspects of reference intervals, in practice their use is still not completely satisfactory. Most of the laboratories have used various methods to calculate statistic-based reference intervals, and they have mainly focused on extracted data, yet its use is considerably limited. We had to deal with the inconvenience of using a number of programs (SPSS or SAS, MS Excel) in order to calculate the results of reference intervals. METHODS: In order to obtain standardized reference intervals, we developed an integrated program that can calculate, by a nonparametric method, reference intervals with using the Clinical and Laboratory Standards Institute (CLSI) processes as its guideline. We also developed a grouping interface that enables users to customize classification of each group (age, gender, blood group, race, etc) when calculating reference intervals. RESULTS: To verify the developed program, we compared the reference intervals of the current data on 281 persons for 8 total areas, and the reference intervals were was already calculated beforehand with by using this new program. As a result, both results perfectly matched. CONCLUSIONS: This integrated program will be convenience for calculating reasonable values through continual datainspection at an inspection lab for calculating reference intervals. The newly developed program will improve the consistency and reliability of the statistics on reference intervals.


Subject(s)
Humans , Racial Groups , Diagnostic Tests, Routine , Phenothiazines , Pyridines , Reference Values , Thiazoles
14.
Journal of Korean Society of Medical Informatics ; : 65-74, 2008.
Article in Korean | WPRIM | ID: wpr-228417

ABSTRACT

OBJECTIVE: This study focuses on the development of a systematic and efficient information system for effective management of patient data in home hospice care. It is easily implemented in the hospice environment and is based on wired and wireless communications along with mobile computing technology. METHODS: The design of this portable home hospice information system was based on an analysis of the services provided by visiting nurses and on the opinions of users, in accordance with the Ministry of Health and Welfare's Guidelines for Cancer Patient Management Program 2005. The system has eight main menus, each of which performs a different function. The system includes the home hospice information system (HHIS), a compact .NET framework, and the health center information system (HCIS). RESULTS: A trial was conducted with three experienced visiting nurses, who each used a personal digital assistant (PDA) loaded with the new system to add patient information. The functions include registering a new patient, performing appropriate nursing service according to established guidelines, based on the patient's condition, and searching data records. The system resulted in a saving of 8.5 minutes in nursing data recording time. CONCLUSION: The findings of this study are expected to help field workers in community nursing to decrease the nursing data recording time by using PDAs.


Subject(s)
Humans , Community Health Nursing , Computers, Handheld , Health Personnel , Hospice Care , Hospices , Information Systems , Nursing Services
15.
Journal of Korean Academy of Nursing ; : 976-985, 2007.
Article in Korean | WPRIM | ID: wpr-80950

ABSTRACT

PURPOSE: The aim of this study was to identify the present situation of hospital infection and route of infection by clarifying the transmission aspect of methicillin-resistant Staphylococcus aureus(MRSA) in a Neurosurgical Intensive Care Unit by analysing genotype. METHODS: MRSA was cultured from twenty five patients with a tracheostomy, twenty five health care workers, and environments in the Neurosurgical Intensive Care Unit of one hospital in D city. Data was collected from December 21, 2004 to November 5, 2005. MRSA isolates representing each genotype were analyzed by spaA typing and a multiplex PCR method capable of identifying the structural type of the staphylococcal cassette chromosome mec(SCCmec) carried by the bacteria. RESULTS: As the same genotype and gene sequence were found among health care workers, patients, and environments, it was assumed that there was cross transmission among them. CONCLUSION: This study suggests that first, as the hospital infection by MRSA between health care workers and patients in the Neurosurgical Intensive Care Unit was due to result of cross transmission and the relevance of transmission between them was verified, it is necessary to take preventive measures and conduct education. Secondly, development of nursing interventions and study of infection are needed. Thirdly, consistent investment in prevention against hospital infections and environmental renovation is needed.


Subject(s)
Humans , Bacterial Proteins/genetics , Drug Resistance, Bacterial , Genotype , Infectious Disease Transmission, Patient-to-Professional , Infectious Disease Transmission, Professional-to-Patient , Intensive Care Units , Methicillin Resistance , Neurosurgery , Polymerase Chain Reaction , Staphylococcal Infections/microbiology , Staphylococcus aureus/drug effects , Tracheostomy
16.
Journal of Korean Academy of Nursing ; : 523-531, 2006.
Article in Korean | WPRIM | ID: wpr-27526

ABSTRACT

PURPOSE: The purpose of this study was to examine the effects of the ulmus root-bark dressing on tissue regeneration in experimentally-induced pressure ulcers in rats. METHOD: A randomized pretest/post-test control group time-series study design was used. Thirty-three male Sprague-Dawley rats were used in this study. The rats were anesthetized with 100mg/kg of ketamine. Pressure ulcers were induced at 140mmHg for three hours using a personally-designed pressing apparatus. For four weeks, the ulmus root-bark dressing was applied every other day in the experimental group (n=18) and a wet gauze dressing in the control group (n=15). For data analysis, the statistical program SPSS WIN 12 was used. The wounds were examined by light microscopy and electron microscopy. RESULT: There were significant statistical differences in the size of the pressure ulcers as time went by(p=0.006). It should be noted that there were no significant statistical differences in the number of capillaries. Using light microscopy the inflammatory infiltration and neovascularization in the dermis in the experimental group emerged densely in the early stages, but recovered rapidly at the latter stages. In addition, the reepithelization of the epidermis occurred earlier than in the control group. By electron microscopy, the cell organelles of the capillary endothelial cells and the basal lamina of capillaries in the experimental group showed a more rapid maturation during the latter stages, compared with the control group. CONCLUSION: According to this study, it can be concluded that the ulmus root-bark dressing is effective regarding the healing of pressure ulcers.


Subject(s)
Animals , Male , Rats , Bandages , Capillaries/ultrastructure , Phytotherapy , Plant Bark , Plant Roots , Pressure Ulcer/drug therapy , Rats, Sprague-Dawley , Regeneration , Treatment Outcome , Ulmus
17.
Korean Journal of Rehabilitation Nursing ; : 129-138, 2005.
Article in Korean | WPRIM | ID: wpr-644925

ABSTRACT

PURPOSE: Irritable bowel syndrome (IBS) is frequently yet little understood disease. Review was performed to promote understanding on the characteristics, pathophysiology, and risk factors of IBS. CONTENT: IBS is characterized by abdom in women and people with higher educational and social background, but there are some controversies. IBS is diagnosed by the Rome II or Manning criteria after excluding organic gastrointestinal diseases. The pathophysioloy is explained by abnormal control mechanism of central and enteric nervous system. Mucosal immunity, secretions, and neurotransmitter are also associated with the hypersensitivity and motility change of bowel function. Stress is known as a major triggering factor and contributed to symptoms. Other risk factors are genetic elements, childhood experiences, inflammation, anxiety, depression, diet, and sleep disorders.


Subject(s)
Female , Humans , Anxiety , Depression , Diet , Enteric Nervous System , Gastrointestinal Diseases , Hypersensitivity , Immunity, Mucosal , Inflammation , Irritable Bowel Syndrome , Neurotransmitter Agents , Risk Factors , Sleep Wake Disorders
18.
Korean Journal of Obstetrics and Gynecology ; : 1966-1969, 2002.
Article in Korean | WPRIM | ID: wpr-114685

ABSTRACT

OBJECTIVES: To characterize the ultrasonographic findings of struma ovarii, a rare ovarian tumor composed solely or predominantly of thyroid tissue or the tumor in which hyperthyroidism results from the ovarian thyroid tissue. MATERIALS AND METHODS: Using ultrasonography, preoperative ultrasonographic findings of pathologically proven struma ovarii in six patients were retrospectively evaluated for the site, size, margin, nature (cystic, solid, mixed), septa, mural nodule, calcification, fat, and metastasis. The findings were compared with pathologic findings. RESULTS: All six were unilateral, and smooth tumor margins, 5 were mixed cystic and solid tumors, regular septa and scattered echogenic spots within cyst. One of our cystic tumor (bilocular) had hyperechoic mural nodules. Calcification was found in one tumor and no fat. Malignant change or metastasis was not any tumor. CONCLUSION: Most cases of struma ovarii occurred unilaterally within ovarian teratomas in premeno- pausal women, Struma ovarii has a characteristic ultrasonographic appearance of a complex mass of multiple cysts and solid components with scattered echogenic spots within cyst.


Subject(s)
Female , Humans , Hyperthyroidism , Neoplasm Metastasis , Retrospective Studies , Struma Ovarii , Teratoma , Thyroid Gland , Ultrasonography
19.
Korean Journal of Anatomy ; : 439-446, 1998.
Article in Korean | WPRIM | ID: wpr-652470

ABSTRACT

It is well known that nerve growth factor (NGF) may serve as a link between inflammation and hyperalgesia. However, there is little information whether brain-derived neurotrophic factor (BDNF), another family of neurotrophin, may related with nociception. In the present study, in situ hybridization was used to evaluate i) the change in the level of BDNF mRNA, ii) colocalization of the trkA mRNA and BDNFmRNA and iii) colocalization of the preprotachykinin (PTT)mRNA and BDNFmRNA following peripheral inflammation produced by an intraplantar injection of Freund's adjuvant into the rat paws. The results obtained were as follows: 1. Peripheral tissue inflammation significantly increased BDNFmRNA levels in the DRG. 2. Many neurons expressing trkAmRNA showed increased expression of BDNFmRNA following peripheral inflammation. 3. Many neurons expressing PTT mRNA showed increased expression of BDNFmRNA following peripheral inflammation. 4. Intraplantar injection of antibody to NGF together with Freund's adjuvant prevent the increase in BDNFmRNA. The present results indicate that the peripheral inflammation induces an increased synthesis of BDNF which is mediated by NGF and BDNF coexist with substance P in the DRG and that BDNF may play an important role related with nociception.


Subject(s)
Animals , Humans , Rats , Brain-Derived Neurotrophic Factor , Diagnosis-Related Groups , Freund's Adjuvant , Ganglia, Spinal , Gene Expression , Hyperalgesia , In Situ Hybridization , Inflammation , Nerve Growth Factor , Neurons , Nociception , RNA, Messenger , Spinal Nerve Roots , Substance P
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