HMGB1 and gastric cancer / 国际肿瘤学杂志

High mobility group box-1 (HMGB1) is a nonhistone nuclear protein.Normally,as one component of the chromatin,HMGB1 regulate life activities such as genetic transcription,recombination and gene repair.HMGB1 can be realeased to the outside of the cell,which can be bound up with cells multiplication,differentiation,migration and the growth of nerve axon.Studies show that HMGB1 is correlated with tumor (s) occurrence,development,invasion and metastasis,such as lung cancer,colorectal cancer,pancreatic cancer and so on.The studies about the relativity between HMGB1 and gastric cancer play an important role in the diagnosis and treatment of gastric cancers.

Mammalian target of rapamycin in gastric cancer / 国际肿瘤学杂志

Mammalian target of rapamycin (mTOR) plays an important role in the regulation of cell proliferation,growth,energy metabolism and so on.Clinical research demonstrate that many tumors have its excessive expression, and the mTOR inhibitors rapamycin can resist the development of gastric cancer.Research of mTOR signaling pathway combined with its upstream and downstream has larger value for the early diagnosis,monitoring curative effect and prognosis.

Study of the relationship of external hydrocephl with brain-injure in the neonate / 中国基层医药

Objective To investigate the relationship of external hydrocephl(EH) with brain-injure in the neonate.Methods By performing on the patients with brain-injure with CT and making the clinical study,the change of brain following injure and its relationship with EH were analyzed.Results Hypoxic-ischemic encephalopathy(HIE) were 36 cases,EH were 19 in the cases,6 get the cerebrospinal symptom;SAH were 22 cases,EH were 15 in the cases,3 get the cerebrospinal symptom;Intracranial hemorrhage were 8 cases,EH were 3 in the cases,3 got the cerebrospinal symptom.Conclusion All the kinds of brain-injure can get EH and the rate of EH with any brain-injure is no different.But the outcome is significantly different.

选择性脊神经后根切断术治疗小儿脑瘫疗效分析 / 中国康复理论与实践

@#目的探讨选择性脊神经后根切断术(SPR)治疗小儿脑性瘫痪(CP)的疗效。方法对我院获取1年完整随访资料的62例SPR患儿进行回顾性分析。结果按AshWorth 5级肌力标准判断,术后下肢肌张力平均下降2.4级,上肢肌张力平均下降0.4级。术后1年患肢肌张力缓解62例(缓解率100%),行走功能和步态改善48例(77.4%)。伴随症状部分改善。结论SPR能有效缓解CP患儿肢体肌张力,改善康复条件。