ABSTRACT
This study was Uesigned to evaluate the reflexive heart rate response to acute blood loss during sodium nitroprusside and prostaglandin E1 induced-hypotension in isoflurane anesthetized dogs. The results were as follows: 1) Reflexive increase in heart rate during induced hypotension was significantly greater in sodium nitroprusside than prostaglandin E1. 2) Reflexive increase in heart rate during induced hypotension was significantly greater prostaglandin E1 induced-hypotension than during that wih sodium nitroprusside. From these results, it suggest that prostaglandin E1 induced-hypotension provides a safer margin than with sodium nitroprusside when rapid bleeding occurs during anesthesia and surgery.
Subject(s)
Animals , Dogs , Alprostadil , Anesthesia , Baroreflex , Heart Rate , Hemorrhage , Hypotension , Isoflurane , Nitroprusside , Pressoreceptors , Reflex , SodiumABSTRACT
This study was Uesigned to evaluate the reflexive heart rate response to acute blood loss during sodium nitroprusside and prostaglandin E1 induced-hypotension in isoflurane anesthetized dogs. The results were as follows: 1) Reflexive increase in heart rate during induced hypotension was significantly greater in sodium nitroprusside than prostaglandin E1. 2) Reflexive increase in heart rate during induced hypotension was significantly greater prostaglandin E1 induced-hypotension than during that wih sodium nitroprusside. From these results, it suggest that prostaglandin E1 induced-hypotension provides a safer margin than with sodium nitroprusside when rapid bleeding occurs during anesthesia and surgery.
Subject(s)
Animals , Dogs , Alprostadil , Anesthesia , Baroreflex , Heart Rate , Hemorrhage , Hypotension , Isoflurane , Nitroprusside , Pressoreceptors , Reflex , SodiumABSTRACT
The authors examined the induntivity of sister chromatid exchanges (SCE) in peripheral lum-phocytes on the personnel working in the operating room and analyzed the factors associated with it to obtain data for their monitoring health status. The results obtained were as follows; 1) Average inductivity of SCE in peripheral lymphocytes of operating room perssonnel exposed to anesthetic gases was 7.85 per cell; it was significantly higher than in those who were not exposed (p0.05). 5) It is possible that the high inductivity of SCE in operating room personnel who both with drink and smoke was due to more the influence of their smoking than their drinking.