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1.
Medical Principles and Practice. 2017; 26 (6): 567-572
in English | IMEMR | ID: emr-197085

ABSTRACT

Objective:The aim of this study was to determine the prevalence of mesenteric panniculitis [MP] and to describe its clinical characteristics, therapy, and outcome


Subjects and Methods: This retrospective study was carried out among patients with MP based on computed tomography [CT] scans from January 2012 to December 2015. The CT images were reanalyzed by study radiologists to confirm the previous MP diagnosis. Patients were divided into 2 groups, i.e., idiopathic and secondary, based on the presence or absence of associated predisposing factors such as trauma, malignancy, autoimmune disorders, ischemia, or previous ab-dominal surgery. The clinical characteristics of the 2 groups, as well as treatments, were assessed


Results: Among the 19,869 CT scans, 36 patients [0.18%] with MP were identified [i.e., 19 [53%] females and 17 [47%] males]. The median age was 54 years [range 26 - 76]. Twenty-four patients [67%] were categorized into the idiopathic group. Malignancy was the predisposing factor in 8 [22%] of those patients. Furthermore, abdominal pain was the cardinal symptom observed in 22 patients [92%] in the idiopathic group. In the idiopathic group, 15 patients [63%] were treated with antibiotics and 16 [67%] were treated with nonsteroidal anti-inflammatory drugs [NSAID]. One unresponsive patient was treated with colchicine. Symptomatic relief was achieved in all of the treated patients


Conclusion: In this study, a symptomatic idiopathic subgroup of patients with MP did not have any associated disorder. The response to treatment with antibiotics and NSAID was effective in most of the patients. Basedon these findings, anti-inflammatory treatments beyond NSAID and surgery should be reserved for patients who are unresponsive to antibiotics and NSAID

2.
Pakistan Journal of Medical Sciences. 2016; 32 (6): 1580-1582
in English | IMEMR | ID: emr-184999

ABSTRACT

Hepatocellular cancer is one of the most common and fatal cancer tumor worldwide. However, the obtained results are questionable in terms of medical treatment of hepatocellular cancer. The muscle, soft tissue and cutaneous metastases of hepatocellular cancer, for instance, are rare and may result from interventional procedures. Seeding of tumor along the biopsy needle upon percutaneous biopsy is a very rare phenomenon. We report a very rare case of a 79 -year- old man, known to be hepatitis C virus carrier with a metastatic tumor in abdominal wall caused by seeding of tumor after three years following a percutaneous biopsy procedure. Even years later, after a biopsy procedure for diagnostic purposes and may be soft tissue metastases. This complication is a very rare condition that should not be ignored but can be observed. The biopsy requirement should be questioned closely and avoided unnecessary biopsy procedures

3.
KMJ-Kuwait Medical Journal. 2012; 44 (4): 316-321
in English | IMEMR | ID: emr-171929

ABSTRACT

Scrotal varicocele is found to be associated with increased spermatozoal reactive oxygen species [ROS] production and decreased seminal plasma antioxidant activity. Our objective was to search for an association between male infertility and gene polymorphisms [PON1, ENOS G894T and Catalase -262C-T]. Controlled prospective study. Ataturk and Yuksek Ihtisas Education and Training Hospitals, Ankara, Turkey. Forty primary infertile men and forty healthy men were included in the study. Patients with clinical varicocele in the study group had no endocrinopathy, no surgery for varicocele / inguinal hernia, and / or no leukospermia. They were non-smokers. Doppler ultrasonography [USG] was performed for the patients. For genetic analysis, 5 ml of venous blood was drawn into tubes containing EDTA from each patient. Gene polymorphism, progressive sperm motion and vein diameter. Existence of gene polymorphisms was statistically important in patients who had clinical varicocele with affected progressive forward motion. We determined statistically significant rate of gene polymorphisms in enzymatic antioxidant defence systems in patients with clinical varicocele, with a diameter of spermatic vein above 2.2 mm and forward progressive sperm motion below 32% [p < 0.001]. These polymorphisms might represent risk factors for Turkish men with clinical varicocele and forward progressive sperm motion defect. This is a pilot study. We intend to continue these studies with larger sample sizes to confirm these findings


Subject(s)
Adult , Humans , Male , Middle Aged , Aryldialkylphosphatase , Catalase , Fertility , Spermatozoa , Infertility, Male , Varicocele , Prospective Studies
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