ABSTRACT
Clinical samples were collected from 120 patients admitted in the Critical Care Center of Kasr El-Aini Hospital, Cairo University. All patients under study were subjected to different types of invasive procedures. Nosocomial infection in CCC developed in 15.8% patients. Respiratory tract infections developed in 40% of the patients after the use of ventilators. Catheter associated urinary tract infection developed in 30% of the patients. 10% of patients developed infections after cardiac catheterization. Central venous line catheterization was followed by infection in 4% of the patients. The predominant organisms isolated were Staphylococcus pyogenes and epidermitis followed by Gram negative bacilli mainly Klebsiella and Pseudomonas. The duration of subjection to different procedures was found to influence the incidence of infection. Sex and age factors did not play any role in changing the incidence of nosocomial infections