Subject(s)
Female , Humans , India/epidemiology , Infant, Newborn , Male , Neutropenia/epidemiology , Pre-Eclampsia/complications , Pregnancy , Prospective Studies , Risk , Sepsis/epidemiologyABSTRACT
Transferable drug resistance, phage type, biotype and minimum inhibitory concentration to different drugs were studied in 50 Salmonella typhi strains isolated during recent outbreak of enteric fever at Calcutta. The antibiotic sensitivity test showed that 44% strains were sensitive to multiple drugs including chloramphenicol. The minimum inhibitory concentrations of the drugs tested were well above the normal level. The transferable drug resistance test suggested that all the resistant strains were carrying transferable multidrug resistant gene containing ampicillin, chloramphenicol, streptomycin, tetracycline resistance factor. From phage typing it was observed that 30% strains belonging to phage type 51, and among them 80% strains were carrying transferable drug resistant factor containing ampicillin, chloramphenicol, streptomycin and tetracycline.
Subject(s)
Disease Outbreaks , Drug Resistance, Microbial , Drug Resistance, Multiple , Humans , India/epidemiology , Microbial Sensitivity Tests , Salmonella typhi/drug effects , Typhoid Fever/drug therapySubject(s)
Age Factors , Child , Child, Preschool , Ethnicity , White People , Female , Hinduism , Humans , Incidence , India/epidemiology , Infant , Islam , Leukemia/epidemiology , Male , Neoplasms/epidemiology , Retinoblastoma/epidemiology , Retrospective Studies , Sex FactorsABSTRACT
There was an outbreak of diarrhoea/dysentery in Naxalbari, North Bengal in August-September of 1992. Ninety-seven cases were investigated. Bacterial pathogens were isolated from stools of 17 cases and the organisms were Salmonella typhimurium (76%), Salmonella enteritidis (12%) and Shigella dysenteriae type 1(12%). A leukaemoid reaction was observed in 4 cases (24%) amongst all 17 patients and they were all children.
Subject(s)
Adolescent , Diarrhea/complications , Disease Outbreaks , Dysentery, Bacillary/complications , Female , Humans , Incidence , India/epidemiology , Leukemoid Reaction/blood , Leukocyte Count , Male , Salmonella Infections/complications , Salmonella enteritidis , Salmonella typhimurium , Shigella dysenteriaeABSTRACT
Six Salmonella senftenberg strains were isolated from blood samples of patients clinically diagnosed to be suffering from enteric fever during the recent outbreak of enteric fever in and around Calcutta. All of them were multidrug resistant including chloramphenicol. The minimum inhibitory concentration (MIC) of the drugs in which they were resistant, were well above the normal level. All these strains were sensitive to cephalexin, gentamicin, furazolidone and ciprofloxacin. The transferable drug resistance test suggested that the strains were carrying transferable drug resistant gene containing ACSTK resistant factor.
Subject(s)
Bacteremia/microbiology , Disease Outbreaks , Drug Resistance, Microbial/genetics , Humans , India/epidemiology , R Factors , Salmonella/drug effects , Salmonella Infections/epidemiologyABSTRACT
The present study was designed to study the clinical behaviour of a recent epidemic of typhoid fever in West Bengal. Of 46 cases studied, 67% (31) had chloramphenicol resistant typhoid fever. The chloramphenicol-resistant cases were comparatively severe in nature with higher complication and mortality rates. Salmonella typhi resistant to chloramphenicol were also resistant to ampicillin, cloxaxillin and cotrimoxazole. Strains of Salmonella typhi sensitive to chloramphenicol retained their sensitivity to these other antimicrobials.