ABSTRACT
Objective: To note characteristic features of patients with nonalcoholic fatty liver disease [NAFLD] diagnosed on ultrasound basis
Design: Descriptive
Place and duration of study DHQ Teaching Hospital, Rawalpindi, from January to June 2003
Materials and Methods: Fifty NAFLD patients diagnosed on ultrasonographic findings were inducted consecutively. Patients with conditions associated with secondary NAFLD were excluded. Clinical and laboratory evaluation of each patient was done to note presence or absence of obesity, hepatomegaly, cholesterol and triglyceride levels, and diabetes mellitus. Obtained data was analyzed using statistical program, SPSS version 10
Results: Of the 50, 54% were female and 46% male. Mean patient age was 42.78 +/- 12.29 years. 66% patients were obese, 56% had hepatomegaly, 28% had elevated cholesterol, 72% had hypertriglycedemia, and 44% were diabetic. All of these features except for hypercholesterolemia were common in females
Conclusion: Obesity, hepatomegaly, diabetes, and hypertriglycedemia are characteristic features of our NAFLD patients that are more common in females
ABSTRACT
Evaluation of upper gastrointestinal [GI] endoscopy in terms of indications, diagnostic efficacy, and diseases diagnosed. Design: Retrospective, observational case series. Place and Duration of Study: DHQ Teaching Hospital, Rawalpindi, from March 1990 to December 2001. Subjects and Patients who underwent upper GI endoscopy in 12 years were included. Upper GI endoscopies were performed according to standard protocol. Endoscopic diagnoses were based on widely accepted criteria. Of the 8481 patients, 4935 [58.2%] were female and 3546 [41.8%] male. Mean patient age was 40.5 years. Dyspepsia [42.6%], upper GI bleed [32.8%], and evaluation of chronic liver disease [10.2%] were common indications of the procedure. An endoscopic diagnosis was possible in 82.6% patients. Varices, gastritis, duodenitis, and combined lesions were common endoscopic diagnosis. Gastritis and duodenitis were most frequent causes of upper GI bleed. We noted more gastric ulcers compared to duodenal ulcers. Females had significantly more normal endoscopies, p-value= 0.02. Upper GI endoscopy is an effective procedure. Dyspepsia evaluation is commonest indication for upper GI endoscopy in our patients. Etiology of upper GI bleed, and incidence of duodenal ulcer compared to gastric ulcer in our patients are different than described in literature. Females have significantly more normal endoscopies