Circulating nitric oxide [NO] in acute attacks of bronchial asthma

Thirty patients with bronchial asthma were included in this study. The airway reversibility in pulmonary function tests including forced vital capacity [FVC], forced expiratory volume in the first second [FEV1] and peak expiratory flow rate [PEFR] was more than 15% after the use of salbutamol inhaler. Venous blood levels of total nitrous oxide metabolites as serum nitrite and nitrate during and in-between acute asthmatic attacks were measured. ABGs were measured during and in-between asthmatic attacks. From the results obtained, it was concluded that the circulating nitric oxide level is suppressed in acute attacks of bronchial asthma, this is promptly reversible with the relief of the acute attacks

Study of pulmonary complications after post mastectomy radiotherapy in patients with cancer breast treated with or without simultaneous adjuvant anti - estrogen

Forty women who were treated with postmastectomy radiotherapy for breast cancer with or without adjuvant tamoxifen treatment were involved in this study. Postmastectomy radiotherapy cases showed slight restrictive ventilatory abnormalities in pulmonary functions, mainly in patients received tamoxifen treatment. The radiological abnormalities developed with postmastectomy radiotherapy were more often easily detected by high resolution computed tomography [HRCT] than by CXR and these abnormalities were significantly higher in patients received tamoxifen treatment. Postmastectomy radiotherapy encountered has in the form of pneumonitis early and late pulmonary lung fibrosis