ABSTRACT
Objective: To determine the antimicrobial activity and entity of several local herbal plants against Acintobacters isolated from trauma patients admitted to a Level-I trauma center
Methods: The antibacterial activities of the Satureja bachtiarica oil and some selected Iranian medicinal plants [Artemisia sieberi and Tanacetum dumosum belonging to the Asteraceae/Compositae; Salvia mirzayanii and Mentha mozaffarianii belonging to the Lamiaceae/Labiatae] were assayed on A. baumannii by microdilution and agar disc diffusion methods. Having obtained the acceptable antibacterial data, the shade-dried aerial parts of the plants were extracted by hydrodistillation method using Clevenger apparatus according to European pharmacopeia for 3 h. The analysis of S. bachtiarica essential oil accompanied by other herbal drug oils were performed by using GC/FID and GC/MS methods
Results: Outcomes revealed that the S. bachtiarica essential oil exhibited the potent antibacterial capability against Acinetobacter strains in comparison with Colistin, as a positive control. For S. bachtiarica, the growth inhibition zone and minimum inhibitory concentration [MIC] values were 21 mm and 0.5 mg/ml, while, for Colistin, the data were in order: 8 mm and 0.016 mg/ml. Consequently, GC/MS outcomes demonstrated that the major components of the essence were carvacrol [48.6%], followed by p-Cymene [16.6%], ã-terpinene [6.9%] and linalool [5.3%]
Conclusion: Based on the considerable inhibitory activity against nosocomial infections by essential oil of S. bachtiarica, it could be considered as the suitable candidate in the food industry and pharmaceutical uses
ABSTRACT
Objective: To record and classify mechanisms of injury and injury severity score [ISS] in trauma patients admitted to the largest trauma center in Southern Iran
Methods: This was a prospective cross-sectional study including all the patients who were admitted to Nemazee hospital from 2009 to 2010. We recorded the trauma injury information of 1217 patients who were admitted to of emergency room of the Nemazee hospital during a 13-months period by means of a standard questionnaire. ISS was then obtained for every single patient
Results: The mean age of patients was 26.6 +/-15.1 [range 1-95] years. The commonest type of trauma including 279 cases [22.9%] was car accident and the least resulted from shotgun injuries in 13 [1.1%] patients. The lowest ISS was due to assault multiple blunt traumas and the highest ISS resulted from shotgun injury. The mean ISS was about 6.3 +/- 1.8 [range 1-66]. Overall, 86 patients had scores above 17 [7.1%]. A total of 69 male patients [7.5%] compared to 17 females [5.7%] had severe injury [ISS>17]. Trauma injuries were significantly more severe in males compared to females [p=0.014]. In the sunny and hot seasons total number of patient was higher. The mean ISS was highest in during spring [p<0.001]
Conclusion: In Shiraz, most of the trauma injuries are occurred during summer and hot weather. Men have greater number of injuries and higher ISS compared to women. The lowest ISS was due to assault multiple blunt trauma and the highest ISS was caused by shotgun injury, and car accident was the commonest cause of trauma with head and neck being the most frequent sites in our patients