ABSTRACT
Objective: this study was designed to compare the gender differences in the pattern of coronary artery lesions in young Pakistani population
Material and Methods: a series of 120 consecutive patients [60 females/60 males], 50 years or less of age, with significant coronary artery lesions, were analyzed and compared for distribution of significant lesions in coronary arteries at National Institute of Cardiovascular Diseases, [NICVD] Karachi
Results: the mean age of female patients was 45 + 5.8 years and male patients 44 + 5.9 years. Single vessel disease [SVD], mid-LAD [left anterior descending artery] lesion and ejection fraction were significantly higher in females. In males, a higher trend for triple vessel disease was observed. In both genders with single vessel disease, the predominant vessel involved was left anterior descending artery. Almost equal incidence of double vessel disease [DVD] was noted in both genders