Correction of facial asymmetry associated with unilateral hypoplastic mandible with monobloc distraction osteogenesis in adult

Facial asymmetrey can be corrected by bimaxillay orthognathic surgery and distraction osteogenesis. We report a case of facial asymmetry which was corrected using monobloc distraction osteogenesis. A monobloc was created using an osteosynthesis fixation device from the zygomatic buttress to the mandible, LeFort I osteotomy was combined with mandiular angle osteotomy and the bloc was distracted using uni-directional distractor

Protective role of taurine on tomaxifen-induced liver damage in rats: a morphological study

To study the protective role of taurine in tamoxifen-induced hepatic steatosis in albino rats. Prospectve experimental study. Department of Anatomy, Khyber Medical College, Peshawar, from July 2011 to November 2011. Four groups of female albino rats, each containing 8 animals, were treated for 21 days as follows: Group A served control, Group B treated with tamoxifen, Group C treated with tamoxifen plus taurine, Group D treated with taurine alone. The animals were weighed at the start and end of treatment and then sacrificed under ether anaesthesia. The livers were fixed in 10% formalin and embedded in paraffin. H and E stained 4 micro thick sections were examined microscopically. There was significant decrease in the body weights of groups B and C as compared groups A and D. Significant increase in the body weights of group C rats in comparison with group B was noted. Histologically the livers of group B animals showed generalized microvesicular and macrovesicular steatosis, with no evidence of hepatocyte necrosis. In group C the fatty change was much less pronounced as compared to group B. The study data suggest that taurine supplementation can reverse / attenuate the hepatic steatosis caused by tamoxifen treatment for 21 days, in albino rats