ABSTRACT
Thiopental sodium and Propofol are two widely-used drugs in the induction of anesthesia in assisted reproductive technology [ART]. However, the side effects and outcome of recovery from anesthesia of these drugs on ART have not been identified yet. This study aimed at investigating the side effects and hemodynamic effects of using thiopental sodium and propofal as well as effects of these drugs on pregnancy outcome in ART cycles. In this double blinded] randomized controlled trial, 90 woman candidate for ART were randomly divided into two groups. 47 patients received Propofol [2.5 mg/kg] and 43 patients received thiopental [5mg/kg] for anesthesia induction. The entry hemodynamic parameters of the patients were documented. During the anesthesia process, hemodynamic parameters were checked at five-minute intervals. The results of the study showed a statistically significant difference between two groups in terms of their response to verbal stimulation [p<0.001], the normalization time of the rate and quality of breathing [p<0.001], nausea [p<0.001], and vomiting [p<0.001]. Also, in comparison with the other group, all these parameters were better in Propofol group. There was found no significant difference between two groups in terms of other variables. Based on the findings of the study, Propofol has fewer known side effects. Vomiting and nausea as two known side effect of anesthesia are significantly lower in patients receiving Propofol than patients who received thiopental
ABSTRACT
Coronary artery diseases [CAD] are leading causes of death in developed countries. Also, 10-15% of elderly people of the United State of America have gallstone. These two diseases have similar risk factors, such as obesity, elderliness, diabetes, hyperlipidemia, and hyper tension. Determining the correlation of coronary artery disease and gallstone is the main Aim of this study. This analytical cross-sectional study was done on 130 patients whom were suspected to CAD and have been referred to Shohadaye Kargar Hospital of Yazd echocardiography department. They have been randomly selected and echo test and sonography have been done for all by expert specialists. Data were analyzed by chi-square, Exact Fisher and Mantel-Haenszel tests. Stress test were negative in 80 [61.53%] and were positive in 50 [38.47%] patients. Of 80 negative stress test subjects, negative gallbladder sonography was observed in 77 [96.25%] patients; while in 3 [3.75] patients gallbladder sonography was positive. Among 50 positive stress test patients, 42 [84%] and 8 [16%] patients had negative and positive gallbladder sonography, respectively. There not found statistically significant association between CAD and gallston [p= 0.022]. Patients who had coronary artery disease, compared with healthy individuals, are at increased risk of gallstones. In men older than 50 years suffering from vague upper abdominal pain, Liver and gallbladder sonography ultrasound is recommended for detection of probable biliary stones