1.
J. venom. anim. toxins
;
3(1): 33-6, 1997. ilus
Article
in English
| LILACS
| ID: lil-276619
ABSTRACT
A very sensitive method for estimating the concentration of crotamine in a solution was developed. This method was based on the based on the time required for the appearance of permanent hyperextension of the rear legs of mice as a function of the dose administered. This method can be used to determine toxin doses as low as 0.32 mg/kg(-1). Its high specificity for crotamine means that it can be used to measure toxin concentrations in the presence of other proteins and polypeptides.