ABSTRACT
PURPOSE: To evaluate the awareness of unmarried Korean women about the relationship between fertility and age with respect to the need to consider oocyte freezing to preserve fertility in cases of delayed marriage and pregnancy. METHODS: Our questionnaires were distributed to a total of 350 unmarried women under 40 years old, consisting of 250 visiting patients and 100 medical workers in Oct. 2010 and Dec. 2010. The questionnaire was composed of 25 multiple choice items as follows: Part I, demographic characteristics; Part II, past history and family history for gynecologic disease; Part III, planning for marriage and pregnancy; Part IV, awareness about fecundity and pregnancy complication according to female age; Part V, willingness toward oocyte freezing for social reasons. RESULTS: The mean age of the women who responded was 29.5 years (range 17~40 years). Eighteen percent answered “very interested” and 23% answered “interested” to the question “Do you want the opportunity to preserve your oocytes to prepare for delayed childbirth for social reasons?” while 47% answered “not very interested” and 11% answered “not at all interested”. There was no statistical difference in age, the number of medical worker, history of gynecologic disease, and familial history of premature ovarian insufficiency between positive responder (n=144, 41.4%) and negative responder (n=204, 58.6%) toward oocyte freezing. CONCLUSION: Even though oocyte freezing is not a widespread procedure in Korean society, oocyte cryopreservation in unmarried women suggests a practical alternative to preserving fertility if its safety, practical effectiveness, and convenience are ensured and communicated to women.
Subject(s)
Female , Humans , Pregnancy , Cryopreservation , Fertility Preservation , Fertility , Freezing , Genital Diseases, Female , Marriage , Oocytes , Parturition , Pregnancy Complications , Single PersonABSTRACT
Rhabdomyolysis is defined as skeletal muscle injury with release of muscle cell constituents into the plasma and may lead to acute renal failure secondary to myoglobinuria. The causes of rhabdomyolysis is diverse:alcohol abuse, primary muscle disease, disturbance of muscle metabolism, sustained seizure, infection, drugs, tox ins, trauma, severe exercise, CO intoxication etc. Rhabdomyolysis may cause acute derangement in electrolyte balance and death. It should be diagnosed earlier and managed properly. We experienced a 49 year-old woman developed acute renal failure and myoglobinuria after alcohol drinking. A kidney biopsy revealed acute interstitial nephritis. In the presence of otherwise unexplained acute renal failure in alcoholic patients, rhabdomyolysis should be considered in the differential diagnosis.
Subject(s)
Female , Humans , Middle Aged , Acute Kidney Injury , Alcohol Drinking , Alcoholics , Biopsy , Diagnosis, Differential , Kidney , Metabolism , Muscle Cells , Muscle, Skeletal , Myoglobinuria , Nephritis, Interstitial , Plasma , Rhabdomyolysis , Seizures , Water-Electrolyte BalanceABSTRACT
Glucose intolerance commonly occurs in patients with renal failure undergoing hemodialysis. whether this mild glucose intolerance contributes to pathogenesis of uremic complication in unknown. Abnormally elevated levels of Hb A1 have been reported in patients with chronic renal failure, whether or not they were undergoing hemodialysis. However serum levels of glycosylated albumin and fructosamine were not evaluated well. Our study was designed to examine fructosamine and glycosylated albumin to assess non-enzymatic glycosylation in patients with chronic renal failure undergoing maintenance dialysis(15 CAPD and 35 hemodialysis patients) and 33 healthy control subjects. Serum fructosamine levels were high in the hemodialysis patients(391.00+/-128.43micromol/L, P<0.05) than control(268.91+/-58.31micromol/L) and CAPD patients(267.7+/-41.27micromo/L). And serum glycosylated albumin levels were also high in the hemodialysis patients(240.40+/-43.99micromol/L, P<0.05) than control (146.22+/-24.88micromol/L) and CAPD patients(172.3+/-42.89micromol/L). After correction for serum albumin concentration, glycosylated albumin was raised in hemodialysis patients(6365.74+/-1307.98micromol/g, P< 0.05) compare with control subject(3259.74+/-581.07micromol/g) and CAPD patients(4988.13+/-1316.47micromol/g). And after correction for serum albumin or protein , fructosmaine was raised in the hemodialysis patients (10282.06+/-3927.37, 3760.00+/-12600.00micromol/g, respectively, P<0.05) compared with control(5705.81+/-1411.36, 1906.67+/-6869.50micromol/g, respectively) and CAPD patients(7752.33+/-2260.16, 869.05+/-5919.35micromol/ g, respectively) This result suggest that dialysis patients have increased protein glycosylation especially in case of hemodialysis patients, most likely reflecting increased non-enzymatic glycosylation of serum protein by impaired glucose tolerance.
Subject(s)
Humans , Dialysis , Fructosamine , Glucose , Glucose Intolerance , Glycosylation , Glycated Hemoglobin , Kidney Failure, Chronic , Peritoneal Dialysis, Continuous Ambulatory , Renal Dialysis , Renal Insufficiency , Serum AlbuminABSTRACT
No abstract available.
Subject(s)
Humans , Dialysis , Kidney Failure, Chronic , Lipid Metabolism , Lipoprotein(a)ABSTRACT
No abstract available.