ABSTRACT
There continuous to be debate about how best to replace bladder function following radical cystectomy. All the usual options currently involve the use of transported intestinal segments, and all have advantage and disadvantages. The impact of each option on patient's needs is an important consideration. The aim of this study was to assess needs for patients undergoing urinary diversion as regarding to physical, psychological, social, and financial needs. The study was carried out at urology unit of El-Demerdash Hospital at Ain shams university and Urology and Nephrology Center of Mansoura University Hospitals. Sample included 100 patients whose undergoing urinary diversion from both sexes. The investigator used Patient's needs assessment questionnaire, and observational checklist to assess patient's response [unverbated needs].The study results revealed that, highest needs were the physical needs with mean +/- SD percentage 96.93 +/- 20.34 followed by unverbated needs with mean +/- SD percentage 13.61 +/- 3.51; psychological problems with mean +/- SD percentage 12.66 +/- 1.94; social needs with mean +/- SD percentage 10.03 +/- 3.31 and financial needs with mean +/- SD percentage 5.88 +/- 0.33. It can be concluded from the study that highest needs were the physical needs followed by unverbated needs; psychological problems; social needs and financial needs. The study recommended the application of guiding educational and cultural programme for patients with urinary diversion to improve their self-care for urinary diversion and urostomy. Emphasizing the importance of more perspective studies to shed light on patient's needs assessment and quality of life for patients with urinary diversion
Subject(s)
Humans , Male , Female , Needs Assessment/statistics & numerical data , Hospitals, University , Surveys and QuestionnairesABSTRACT
Aim: The present study aims to determine the antimicrobial resistance genes and some virulence factors produced by clinical isolates of E. coli and S. pyogenes isolated from different sources
Methods: A total of 60 E. coli and 42 S. pyogenes were studied for antibiotic susceptibility pattern, resistance genes, different resistance enzymes production and some virulence factors such as serum resistance, haemolysin, bacterial ability for colonization, haemagglutination, gelatinase, streptokinase and streptodornase
Results: Nearly 79.4% of the isolates are multiple resistant as they were resistant to all antimicrobial classes used in this study. All E. coli isolates and only 2 S. pyogenes were beta-lactamase producers. Detection of bla-TEM gene reveled that it was amplified on plasmid DNA of 23 isolates out of 25 E. coli isolates. AGIEs prepared from 19 E. coli and 11 S. pyogenes isolates exhibited variable inactivation percentages on different aminoglycosides. Chloramphenicol acetyltransferase [CAT] enzyme was detected among 55% of E. coli isolates. Gyr A gene was successfully amplified by a specific primer set on plasmid DNA of 36 isolates out of 39 tested E. coli isolates which were quinolone resistant. bla-TEM gene was amplified on plasmid DNA of 23 isolates out of 25 B-lactam resistant E. coli isolates. While for S. pyogenes, Gyr A was detected and amplified on genomic DNA of 14 quinolone resistant isolates and bla-TEM was detected and amplified on genomic DNA of 28 B-lactam resistant isolates. Among 60 E. coli isolates, 42 [70%] were serum resistant, 20 [33.3%] showed mannose-resistant haemagglutination, 16 [26.7%] showed mannose-sensitive haemagglutination, 37 [61.7%] were slime producers, 10 [16.7%] were hemolytic and none of E. coli isolates was positive gelatinase producer. Among 42 S. pyogenes isolates, streptodornase production was detected in 28 [66.7%] of S. pyogenes isolates while streptokinase activity was detected in 23 [55%] of S. pyogenes isolates
ABSTRACT
To investigate the relationship between the level of estradiol in non menopausal women, with knee osteoarthritis [O.A], and the clinical and radiological parameters of disease severity. This study comprised 36 non menopausal female patients with knee osteoarthritis diagnosed according to the American College of Rheumatology criteria for primary knee OA. Ten healthy females matched for age served as a control group. All patients underwent clinical evaluation of disease symptoms and signs. Pain was visual analogue scale [VAS]. Standard radio graphs of knee joints were classified according to Kellgren/Lawrence score [K/L score]. Blood samples were obtained from patients and controls for ELICA quantitative determination of serum levels of 17-beta estradiol [E2]. The mean VAS score was 6.17+1.23. According to K/L score, only three patients [8.3%] were of grade 2, twenty one patients [58.3%] were of grade 3 whereas twelve patients [33.3%] had grade 4 affection of the knee. The mean level of serum E2 in patients was 45.57+ 19.04 pg/ml while that of the control group was 80.4+2.79 pg/ml. These results proved that serum levels of E2 showed a highly significant decrease among osteoarthritic patients compared to control levels. Patients with positive effusion, deformity, limitation of range of motion and muscle wasting showed significantly lower levels of serum E2. There was a negative significant correlation between serum levels of E2 and both of the VAS and K/L score. It was concluded that non-menopausal patients with knee osteoarthritis have low serum estradiol which can be considered as a marker of clinical and radiological severity