ABSTRACT
Purpose To investigate MRI features of encephalitis in children with severe hand-foot-mouth disease (HFMD). Materials and Methods The MR images of 85 cases of clinically diagnosed encephalitis in severe HFMD patients were retrospectively reviewed. Results In 85 patients, plain MRI was negative in 28;57 cases were positive including 10 cases showing punctate or patchy lesions in cerebral hemisphere, callosum, thalamus and cerebellar vermis with isointensity or slightly hypointensity on T1WI, isointensity or slightly hyperintensity on T2WI, and hyperintensity on T2FLAIR and DWI. In 47 cases, the lesions were located in the brainstem, tegmentum of pons and medulla oblongata. MRI features included symmetric high signal on DWI in posterior portions of brainstem, hypointensity or isointensity on T1WI and hyperintensity or isointensity on T2WI and T2FLAIR (n=17);patchy long T1, long T2 signal in posterior portions of brainstem, normal or mild hyperintensity on DWI, hyperintensity on T2FLAIR (n=30); lesion extending around the fourth ventricle in 9 patients, one of which involved bilateral cerebral peduncles. Conclusion Encephalitis in children with severe HFMD has characteristic MRI features. The lesions are mostly located in the posterior portion of the brainstem. DWI and T2FLAIR can better detection lesions.
ABSTRACT
Objective To analyze routine CT and high-resolution CT (HRCT) characteristics of acute miliary pulmonary tuberculosis (AMPT) and miliary lung metastases (MLM). Methods CT and HRCT data of 25 patients with AMPT and 30 with MLM were retrospectively reviewed; nodular characteristics and other complicated findings were observed. Results No difference was found in size, density, distribution and margin of miliary nodule between AMPT and MLM (P＞0.05). Ground-glass opacities and consolidation in AMPT was more than those in MLM (P＜0.05), while multiple small cavitates, interlobular septal thickening, pleural thickening and lymph node increasing were more obvious in MLM than in AMPT (P＜0.05). Conclusion CT characteristics of AMPT and MLM are different and contribute to the differential diagnosis of the two diseases.