ABSTRACT
Clinical retinopathy eventually develops in the majority of insulin dependent diabetics during several decades of metabolic abnormality. Early structural lesions short of clinical significance may occasionally be detected in children much more frequently, however, after puberty. Major factors modulating the development of retinopathy are duration of diabetes, glycemic control and blood pressure.
Subject(s)
Adolescent , Adult , Child , Diabetes Mellitus, Type 1/complications , Diabetic Retinopathy/prevention & control , HumansABSTRACT
Acne fulminans e uma forma particularmente severa de acne que acomete pacientes jovens e que, por seu quadro clinico-laboratorial, pode ser separada dos outros tipos Sao apresentados onze pacientes com esta doenca. Alem dos aspectos diagnosticos e clinicos, e discutido, com especial atencao, o tratamento com o acido 13-cis-retinoico (isotretinoina, RO 4-3780, Accutane: EUA, Roaccutan: Europa) que apresentou em todos os pacientes uma melhora substancial